Parts of the Forebrain Flashcards
What regions make up the Forebrain?
The Forebrain contains regions derived from the Diencephalon and Telencephalon as follows:
Diencephalon derivatives: Thalamus, Hypothalamus, Posterior Pituitary Gland, Pineal Gland
Telencephalon derivatives: Cerebral Cortex, Basal Ganglia, Limbic System
Define/describe the function of the Thalamus:
The Thalamus is a portion of the Forebrain that serves as a relay and sorting station for sensory information, and then transmits the information to the cerebral cortex.
Define/describe the function of the Hypothalamus:
The Hypothalamus is a portion of the Forebrain that controls homeostatic and endocrine functions by controlling the release of pituitary hormones.
The Hypothalamus is subdivided into the lateral hypothalamus, ventromedial hypothalamus and anterior hypothalamus.
The hypothalamus is also the primary regulator of the Autonomic Nervous System and is important in drive behaviors such as hunger, thirst & sexual drive.
Define/describe the function of the Lateral Hypothalamus (LH):
The Lateral Hypothalamus is referred to as the hunger center because it has special receptors thought to detect when the body needs more food or fluids.
In extirpation of lab rats, destruction of the LH would cause the lab rats to die from dehydration/starvation due to their refusal of eating/drinking and if not force-fed through tubes.
Define/describe the function of the Ventromedial Hypothalamus (VMH):
The Ventromedial Hypothalamus is identified as the ‘satiety center’ and provides signals to stop eating.
Studies have shown that brain lesions in this region usually led to obesity.
Define/describe the function of the Anterior Hypothalamus:
The Anterior Hypothalamus is the structure that controls sexual behavior and regulates sleep & body temperature.
In extirpation of lab rats, stimulation of this region resulted in the lab rats mounting everything including inanimate objects.
In extirpation of lab rats, destruction of this region resulted in permanent inhibition of sexual activity.
Mnemonic:
What are the (Four) Functions of the Hypothalamus?
Hint: The Four F’s
The Four Fs:
- ) Feeding
- ) Fighting
- ) Flighting
- ) (Sexual) Functioning
Mnemonic:
What is the function of the Lateral Hypothalamus?
Hint: LH
When the Lateral Hypothalamus (LH) is destroyed, one Lacks Hunger.
Mnemonic:
What is the function of the Ventromedial Hypothalamus?
Hint: VMH
When the VentroMedial Hypothalamus (VMH) is destroyed, one is Very Much Hungry.
Mnemonic:
What is the function of the Anterior Hypothalamus?
Hint: AH
When the Anterior Hypothalamus is destroyed, one is Asexual Honestly.
Define/describe the function of the Posterior Pituitary Gland:
The Posterior Pituitary Gland is the “master gland” of the endocrine system comprised of axonal projections from the hypothalamus that triggers hormone release in other endocrine glands.
The PPG releases antidiuretic hormone (ADH aka vasopressin) and Oxytocin.
Define/describe the function of the Pineal Gland:
The Pineal Gland is a brain structure located near the thalamus that secretes melatonin.
Melatonin regulates circadian rhythms.
The Pineal Gland is a key player in several biological rhythms and receives direct signals from the retina for coordination with sunlight.
Define/describe the function of the Basal Ganglia:
The Basal Ganglia is a portion of the Forebrain that coordinates muscle movement and routes information (via the Extrapyramidal Motor System) from the cortex to the brain and spinal cord.
Define/describe the function of the Extrapyramidal System:
The Extrapyramidal Motor System is part of the basal ganglia that modulates motor activity.
It gathers information about body position and carries this information to the CNS, but does not function directly through motor neurons.
The Basal Ganglia help make our movements smooth and our posture steady.
How does Parkinson’s Disease affect the Basal Ganglia?
Parkinson’s Disease is one chronic illness associated with destruction of portions of the basal ganglia and is typically characterized by jerky movements and uncontrolled resting tremors.
The Basal Ganglia may also play a role in schizophrenia and OCD.
Define/describe the function of the Limbic System:
The Limbic System is a portion of the cerebrum that is comprised by a group of interconnected structures looping around the central portion of the brain and is primarily associated with emotion and memory.
The Limbic System’s primary components include the Septal Nuclei, Amygdala and Hippocampus.
Describe/define the function of the septal nuclei:
The Septal Nuclei is one of the primary pleasure centers in the brain.
Stimulation of the septal nuclei is reported to be intensely pleasurable and there is a suggestive association between these nuclei and addictive behavior.
Define/describe the function of the Amygdala:
The Amygdala is a structure that plays an important role in defensive and aggressive behaviors including fear & rage.
Damage of the Amygdala has shown markedly reduction in aggression and fear reactions. Additionally, lesions in the Amygdala resulted in docility and hypersexual states.
Define/describe the function of the Hippocampus:
The Hippocampus plays a vital role in learning and memory processes. The Hippocampus helps consolidate information to form long-term memories and can redistribute remote memories to the cerebral cortex.
The Hippocampus communicates with other portions of the Limbic System through the Fornix.
Define/describe the function of the Fornix:
The Fornix is a long connection from the Hippocampus that connects to other nuclei in the Limbic System.
What is Anterograde Amnesia?
Anterograde Amnesia is a form of memory loss in which new long-term memories cannot be established.
What is Retrograde Amnesia?
Retrograde Amnesia is a form of memory loss which impacts long-term memories of events prior to the time of injury.