Part I Biochemical Profile Flashcards
This is the primary energy source
Glucose
Blood glucose levels are held in a constant range by
Regulatory hormones and metabolic activiyt
Glucose disorders result in
hypoglycemia and hyperglycemia
This decreases blood glucose
insulin
This is secreted in fasting state to increase glucose levels
glucagon
This is secreted after eating when glucose levels are high
insulin
This is the classic hyperglycemia disorder
DM
FBG range
70-99mg/dl
Symptoms of diabetes
3 Ps (polyspias, polyuria, polyphagia
blurred vision
nausea
This (along with glucose tolerance test) should be ordered if suspted DM
A1c
OGTT test are usually done at this time interval
2 hr
This test is done to determine if the bllod sugar levels in DM patients are under controll
A1c=glycohemoblobin
The normal range for a A1c test is
4%-6%
Test Normal ranges
70-99 Fasting glucose
<140 OGTT
<5.7 A1c
Prediavetes ranges
100-125 Fasting Glucose
140-199 OGTT
5.7-6.4 A1c
Diabetes test ranges
> 126 FG
200 OGTT
6.5 A1c
This type of DM is insulin dependent
type 1
This type of Dm is non insulin dependent and is MC
type 2
Gestional Diabetes is tested at
24-28 weeks
This is a shortage of insiulin
Diabetic coma
Two types of hypoglycemia that can occur in non diabetic patients
Reactive
Fasting
This type of non diabetic hypoglycemia occurs within 4 hours after meal
reactive
This type of non diabetic hypoglyceima is usually related to underlying disease
Fasting
This is the name given to the symptoms that are known or likely to be caused by hypoglycemia
Whipples Triad
This represents elevated blood levels of BUN
Azotemia
This is a better indicator of renal disease than BUN
Creatinine
Protein is increased in these diseases
MM
Dehydration
Chronic infections
Malignancies
Protein is decreased in
live disease
kidney ds
malabsorption
This is 60% of total protein and made in the liver
Albumin
This helps regulate collodial osmotic pressure and transports important blood constituents
Albumin
Albumin is a measure of
liver function
Albumin is increased in this disease
dehydration
This is the key building block of antibodies and some are used for transport
globulins
CRAB
Calcium elvated Renal Disease Anemia Bone lesions (MM)
Hypercalcemia is associte with this bone cancer
MM
This measures the excretory unction of the liver
Bilirubin
Increase in this are highly specific for disease of the liver or bile ducts
Conjugated bilirubin
These tissues have the highest concentration of alkaline phosphtase
liver
bone
Dectection of this enzyme is important in determining liver and bone disorders
ALP
ALP is assocbone activityiated with this can of
growth
Highest levles of acid phostphatse are found in
prostate gland
This measurement has a hoogh possibilty of prostate cancer
> 10 PSA
This is the change in PSA over a period of time
PSA velocity
This enzyme partcipates in transfer of AA and peptides across cell membranes
GGTP
GGTP is used to detect
liver dysfunction
GGTP is not a detor of
bone disease
Calcium levles can elevate
Parathyroid function
The MC cause of hpercaleima is
Primary hyperparathyroidism
Radiographic findgins for HPT
subperiosteal reabsobtion
brown tumors
Medial Arterial calcification is very common in people wtih
diabetes
chronic renal failure
Phosphrus has an inverse relationhip with
Calcium
This is most specific for pancreatitis
amylase
Acute Pancreatitiscauses elevated
Lipase
These two correlate to damage to the pancreatic ells
Amylase
Lipase
CPK test are done for
Cardiac muscle injury
High Cholesterol is associated with
Hyperlipedemia
Low cholesterol levers are associated with
liver disease
LDLs shpuld be less than
130mg/dl
This is the most sensitive and specific test for mycardial damage
Cardiac troponin
Thyroid is regulated by
TSH (from pituary gland)