Part I and II Flashcards
Arrhythmia
a disturbance in or loss of regular rhythm. (2) especially, any variation from the normal rhythm of the heartbeat, it may be an abnormality of either the rate, regularity, or site of impulse origin or the sequence of activation. The term encompasses abnormal regular and irregular rhythms as well as loss of rhythm.
Automaticity
the state or quality of being automatic. (2) the capacity of a cell to initiate an impulse, such as depolarization, without an external stimulus.
Biphasic
having two phases; in electrocardiography, having an impulse vector that is no moving exactly perpendicular, nor parallel, to the “observing” electrode, resulting in deflections that are both above and below the isoelectric baseline.
Bradycardia
slowness of the heartbeat, as evidenced by slowing of the pulse rate to less than 60 beats per minute.
Chronotropy
referring to the time or rate, as the rate of contraction of the heart. Something that causes positive chronotropy will result in an increase in heart rate (e.g., epinephrine, atropine), while a negative chronotrope causes a decrease in heart rate (e.g. beta-blockers, calcium channel blockers).
Conductivity
the capacity of a body to transmit a flow of electricity or heat; it is the conductance per unit area of the body. When expressed in figures, electrical conductivity is the reciprocal of resistivity.
Depolarization
1) the process or act of neutralizing polarity. (2) in electrophysiology, the reversal of the resting potential in excitable cell membranes when stimulated, i.e., the tendency of the cell membrane potential to become positive with respect to the potential outside the cell.
Dromotropy
referring to the conductivity of a nerve fiber, such as the rate of depolarization, thus affecting the speed at which impulse transmission flow. Positive dromotropy refers to a state in which impulse transmission is made faster (e.g., epinephrine, atropine), whereas a negative dromotrope causes a reduction in the velocity of such transmission (e.g., digitalis, adenosine).
Ectopic
arising in an abnormal site or tissue; in electrophysiology, the origin of an electrical impulse from a site outside of the sinoatrial node (SA node).
Excitability
(1) irritability. (2) the capacity of a cell to depolarize and form an action potential when in the presence of a stimulus stronger than a threshold value.
Inotropy
referring to the force or energy of muscular contraction. Something causing positive inotropy will result in an increase in the contractile force (e.g., dopamine, dobutamine), while a negative inotrope leads to a reduced or weaker degree of contractility (e.g., beta-blockers, calcium channel blockers).
Interval
the space between two objects or parts, the lapse of time between two recurrences or paroxysms.
Intrinsic/inherent
situated entirely within or pertaining exclusively to a part; implanted by nature; innate.
Reentry
reexcitation of a region of cardiac tissue by a single impulse, continuing for one or more cycles and sometimes resulting in ectopic beats or tachyarrhythmias. It can exist over either an anatomical or a functional area of slowed impulse conduction and requires also refractoriness of tissue to stimulation and an area of unidirectional block to conduction.
Refractory period
period of time following depolarization of a cell in which there is a state of resistance to subsequent stimulation.