Part A DM Insulin (Lecture 2) Flashcards
When does basal insulin lower glucose?
Between meals and over night (fasting)
Basal insulin account ____% of daily insulin needs
50%
Which insulins are basal insulin products?
*NPH &DGD
-NPH
-Degludec (LA)
- Glargine (LA)
- Detemir (LA)
Basal insulin has a _____ onset
Slow (11-24 hours/longer)
Basal insulin color?
Clear solution
Is basal insulin peakless?
YES
Bolus insulin has a ____ onset & _____ DOA
Rapid & Shorter
When does bolus insulin lower glucose?
During and after meals (post prandial hyperglycemia)
Bolus insulin accounts for ______% of total daily insulin requirements at each meal
10-20%
Which are rapid acting mealtime bolus insulins?
*GAL
-Glulisine
- Aspart
- Lispro
Which are short acting mealtime bolus insulins?
*SR
-Regular insulin
For Type 1 DM what does insulin replace?
Replaces normal pancreatic hormone production
In Type 2 DM how is insulin utilized?
Insulin complements other oral drugs/ and or to supplement endogenous insulin release
Insulin component of Humilin/Novolin 70/30
70% NPH & 30 regular
Insulin component of Humilin 50/50
50 NPH & 50 Regular
Insulin component of Humalog 75/25
75 Lispro protamine & 25 Lispro
Insulin component of Humalog 50/50
50 Lispro protamine & 50 Lispro
Insulin component of Novolog 70/30
70 Aspart protamine & 30 aspart
What are the 2 premixed insulins with GLP-1RA?
- Glargine/ lixisenatide
- Degludec/ Liraglutide
How do you initiate basal insulin for DM?
Begin with a single insulin dose @ bedtime (10-20 units). Use *Degludec, Glargine, Detemir, or NPH
What should we target to correct first?
Fix fasting blood sugars first!
Adjust and increase insulin dose every ______ days as needed to target FBG goal
3-4 days
What is the FBG glucose goal?
80-100
Titrate basal insulin dose by 2 units if FBG are between ______?
100-120 mg/dL
