part 4 (b-oxidation) Flashcards

1
Q

A series of five enzyme-catalyzed reactions
that cleaves carbon atoms two at a time from the carboxyl end of a fatty acid.

A

B-Oxidation

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2
Q

What is the first reaction of B-Oxidation

A

The fatty acid is activated by conversion to an Acyl CoA

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3
Q

What is the second reaction of B-oxidaion

A

Oxidation by FAD of the a,b carbon carbon single bond to a carbon carbon double bond

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4
Q

What is the enzyme responsible for the second reaction of B-Oxidation

A

Acyl-CoA dehydrogenase

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5
Q

What is the third reaction of B-oxidation

A

Hydration of the Carbon carbon double bond to a 2° alcohol

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6
Q

What enzyme is responsible for the third reaction

A

Enoyl-CoA hydratase

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7
Q

What is the fourth reaction of B-Oxidation

A

Oxidation of the 2° alcohol to a ketone

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8
Q

What enzme is responsible for the fourth reaction

A

B- Hydroxyacyl-CoA Dehydrogenase

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9
Q

What is the fifth reaction of B-oxidation

A

Cleavage of the carbon chain by a molecule of CoA-SH

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10
Q

What enzyme is responsible for the fifth reaction of B-Oxidation

A

Thiolase

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11
Q

This cycle of reactions (B-Oxidation) is then repeated on the shortened fatty acyl chain and continues until the entire fatty acid chain is degraded to ______

A

Acetyl CoA

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