part 4 Flashcards
An enzyme-regulation process where the product of a series of enzyme-catalyzed
reactions inhibits an earlier reaction in the sequence.
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An inactive form of an enzyme that must have part of its polypeptide chain hydrolyzed and
removed before it becomes active
Proenzyme (zymogen)
give me an example of active and inactive enzyme
-Triypsnogen (inactive
-Triypsin (Active)
Enzyme regulation based on an event occurring at a place other than the active
site but that creates a change in the active site.
Allosterism
An enzyme regulated by this mechanism is
called an ________
Allosteric enzyme
Inhibition of an allosteric
enzyme.
Negative modulation
Stimulation of an
allosteric enzyme.
Positive modulation
A substance that binds to an allosteric enzyme.
Regulator
The process of affecting
enzyme activity by covalently modifying it.
Protein modification
Give an example of phosporylation
when Pyruvate Kinase turns into Pyruvate kinase Phophate
An enzyme that occurs in
multiple forms; each catalyzes the same reaction.
Isoenzyme (Isozymes
Give an example of isoenzyme
LDH (Lactate dehydrogenase)
- tetramer is H and M
H=heart muscle
M= Liver and skeletal muscle
