Part 2: Types of Studies Flashcards

1
Q

What are the 4 different studies?

A
  1. RCT
  2. Cohort
  3. Cross-sectional
  4. Ecological
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is a longitudinal study?

A

A study which goes through a period of time (over a long period of time)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the opposite of longitudinal study?

A

Cross sectional study (one point in time)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which occurrence type can longitudinal studies be associated with?

A

Incidence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which occurrence type can cross sectional be associated with?

A

Prevalence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which studies out of the 4 are longitudinal?

A

RCT
Cohort
Could be Ecological

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which studies out of the 4 are cross sectional?

A

Cross-sectional

Could be Ecological

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the usual study objective of RCT?

A

Investigate the effects of different interventions (exposures) on dis-ease incidence in different group of individuals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the usual study objective of Cohort studies?

A

Investigate associations (effects) between risk factors (exposures) and dis-ease incidence in different groups of individuals.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the usual study objective of Cross-sectional studies?

A

To measure dis-ease prevalence in defined groups of individuals.

Investigate associations between exposures and dis-ease prevalence in the groups.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the usual study objective of Ecological study?

A

Investigate associations between exposures and dis-ease prevalence or incidence in different groups of populations.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which studies have individuals?

A

RCT
Cohort
Cross-sectional

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which study sees groups of populations rather than individuals?

A

Ecological

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the most useful application of the RCT?

A

Effect of interventions like in:

  • New therapies
  • Drugss
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the most useful application of the Cohort?

A

Studying the causes of dis-ease incidence or the effects of interventions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the most useful application of the Cross-sectional?

A

Measuring the prevalence/burden of dis-ease in different groups and populations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the most useful application of the Ecological?

A

Studying trends and causes of dis-ease incidence and prevalence

18
Q

Which studies are experimental?

A

RCT

Could be Ecological

19
Q

What is the opposite of experimental?

A

Observational

20
Q

Which studies are observational?

A

Cohort
Cross-sectional
Could be Ecological

21
Q

What does observational mean?

A

That the study undertakers are only viewing the participants, not forcing them to use anything (ethical)

22
Q

What does experimental mean?

A

We do not know the outcome (like a new drug) so it could be bad or good but we are essentially experimenting on people in the RCT trials

23
Q

How is RCT allocated?

A

Random

24
Q

How is Cohort study allocated?

A

Measurement

25
Q

How is Cross sectional allocated?

A

Measurement (usually by questionnaire or survey)

26
Q

How is Ecological allocated?

A

Could be random or measurement

27
Q

What does random allocation give rise to?

A

No confounding, allocation non random error

28
Q

What does measurement error give rise to?

A

Confounding (allocation non random error)

29
Q

Which studies have confounding?

A

Cohort
Cross-sectional
Ecological

30
Q

What is the weakness of longitudinal studies?

A

Long time give rise to

  • maintenance error
  • also $$$$$$$$$$$
31
Q

What gives rise to cross sectional (quick) studies?

A

Quick,

  • no maintenance issue
  • cheap as $
32
Q

What is the main strength of RCT? (1)

A

Limited confounding

33
Q

What is the main strength of Cohort studies? (2)

A

Usually cheaper than RCT (even though longitudinal)

E measured before O so NO recall bias

34
Q

What is the main strength of Cross-sectional studies? (3)

A

Cheap

Quick, no follow up so NO MAINTENENCE

Best design for assessing prevalence/burden of dis-ease in population

35
Q

What is the main strength of Ecological? (3)

A

Cheap

Quick

Efficient for rare outcomes

36
Q

If a study is generally quick (no follow up) what does this have a positive for?

A

No maintenance non random error

37
Q

What are the main weaknesses of RCT?

A

Ethical limitations

$$$$$$$$ so normally small participants so more random error and could be statistically insignificant

Maintenance error common

38
Q

Which studies have follow ups?

A

RCT
Cohort
Could be ecological if it is a collection of RCT’s

39
Q

What can follow up’s lead to (the weakness)

A

Maintenance non random error

40
Q

What are the main weaknesses of Cohort?

A

Confounding (due to measurement allocation)

Maintenance error (long term studies because exposure is not controlled by the invesitgators)

41
Q

What is the main weakness of Cross-sectional studies?

A

Uncertain time sequence so reverse causality

If period prevalence, can be subject to recall bias

Confounding (allocation is by measurement; survey)

42
Q

What is the main weakness of Ecological studies?

A

Confounding very common