Part 1 - anomalies involving number, size and shape of teeth Flashcards
List the stages in tooth development (8 stages)
Stages of tooth development:
1–4 = Growth (bud, cap, bell)
4–6 = Eruption (apposition and calcification, pre- and post-emergence)
6–8 = Attrition (early and later signs)
- Initation (bud stage) at 6 weeks
- Proliferative (cap stage)
- Morphodifferentiation and histodifferentiation (bell stage)
- Aposition and calcification
- Pre-emergence
- Post-emergence
- Early signs of attrition
- Later signs of attrition
Describe the abnormality which may occur due to disrupted dental lamina formation
Abnormality in number of teeth
Describe the abnormality which may occur due to disrupted morphodifferentiation
Abnormality in tooth size and shape
Describe the abnormality which may occur due to disrupted matrix deposition and mineralisation
Abnormality in tooth structure
Define anodontia
No teeth (very rare)
Define hypodontia (or partial anodontia/oligodontia)
Fewer than normal number of teeth
Define hyperdontia
More than the normal number of teeth
Recall the rate and pattern of hypodontia in the permanent dention
Rate of hypodontia in permanent dentition (2-10%)
Most likely third molars (35% < 1), then maxillary lateral incisors followed by lower second premolars.
Familial tendency
Recall the national tendency of hypodontia
National tendency (Japan / Sweden – L1’s)
Recall the formation of tooth bud for deciduous and permanent teeth
Successional tooth bud:
Tooth germ (bud) of permanent incisors, canines and premolars form as a result of proliferative activity within the dental lamina, lingual to the deciduous tooth germ (ABCDE)
If the developing permanent molars have no deciduous predecessor (i.e. permanent molars 678), their tooth germs originate directly from the dental lamina.
Recall the most common clinical signs of hypodontia (3 points)
- Retained deciduous teeth, well after the date of normal exfoliation
- Spaces
- Infraoccluding deciduous teeth
Recall the X-ray investigations required for suspected hypodontia
Radiographic images required for assessment of missing teeth (e.g. suspected hypodontia) are:-
- OPG X-Ray
- Upper occlusal X-ray
(If no upper occlusal X-rays are available P/A’s will be an alternative – but not the ideal)
Describe this case and name one differential diagnosis
Retained deciduous teeth - ?hypodontia:
Spacing
Infraoccluded deciduous teeth
Missing maxillary lateral incisors
Describe the buccal segment teeth and list 8 possible aetiological factors
The teeth are infraoccluded teeth. Aetiological factors:
- Ankylosis
- Impaction
- Absence of a permanent successor
- Trauma causing damage to Hertwigs epithelial root sheath
- Infection, chemical or thermal irritation
- Failure in bone growth
- Abnormal tongue pressure.
- A genetic aetiology has also been suggested as observed in siblings
Name of differential diagnosis from this radiograph
Hypodontia - more than normal number of teeth missing
What are some clinical considerations of infraocclusion?
- Orthodontic assessment (IOTN = 5s)
- Extractions
- Ankylosed
- Impacted
- Advanced restoration?
Name 3 conditions associated with missing teeth (hypodontia)
- Hereditary ectodermal dysplasia
- Cleft lip and palate
- Down’s syndrome (3rd molars absent 90% cases)
Describe hereditary ectodermal dysplasia and the tissues affected
- Hair (absent / thin and sparse)
- Small, conical teeth (sometimes missing but rarely 100% missing)
- Reduction in/absence of sweat glands (dry smooth skin)
- Decreased skin pigment/colour
- Abnormal fingernails
- Small maxilla (maxillary hypoplasia)
- Poor hearing and vision, decreased tear production
Name this condition
Hereditary ectodermal dysplasia
Name this condition
Hereditary ectodermal dysplasia
Describe the possible inheritance patterns of hereditary ectodermal dysplasia (3 points)
- X-linked recessive
- Autosomal dominant
- Autosomal recessive
Recall the incidence of cleft palate
Boys vs girls (freqency and severity)
Unilateral vs bilateral
Left side vs right side
Europe vs Africa
Boys are more commonly affected than girls 3:2
More boys experience the more severe cleft lip and palate 2:1
75% of clefts unilateral
The left side is more than right side
Europeans 1:750
Less frequent in African populations 1:2000
Recall the aetiology (causes) of cleft lip and palate
Unknown what causes defects – many factors suggested:-
- Genetics (4% increase of CL&P if sibling or parent has CL&P)
- Environment
- Drugs (corticosteroids, phenytoin)
- Infections in pregnancy (e.g. rubella)
- Alcohol consumption/ smoking / some dietary deficiencies (e.g. folic acid / vitamin A)
- Maternal age
List 10 dential issues associated with cleft lip/palate cases
- Can be hypodontia OR in rare cases hyperdontia.
- Presence of natal and neonatal teeth
- Microdontia
- Fused teeth
- Enamel hypoplasia
- Poor periodontal support
- Gemination and dilacerations
- Anterior and posterior cross bite
- Class III tendency
- Spacing and crowding
Which chromosome is most commonly associated with Down’s Syndrome (95% of cases)?
Trisomy 21 (3rd copy of chromosome 21) most common cause (95%).
Recall the incidence of Down’s Syndrome
1 in 700 births but closely associated with the maternal age
(it increases to 1 in 25 of mothers over the age of 45yrs.)
Recall 7 developmental issues leading to oral complications in Down’s Syndrome
- Hypoplasia of the mid-face - an underdeveloped maxilla means that most are Class III – and also have a protrusive tongue
- Poorly developed paranasal sinuses are common due to the small maxilla – and breathing can be difficult.
- Often have an anterior open bite and in many cases the lateral incisors are missing
- Teeth can appear smaller (microdontia) and can also be missing (hypodontia)
- Delayed eruption
- Relatively low incidence dental caries, however often rapidly progressing periodontal disease is associated
- They have a heavily fissured and enlarged tongue
Recall the clinical considerations of hypodontia for a patient with Down’s Syndrome
- Do nothing
- Direct restoration (disguise)
- Orthodontics with or without restoration
- Restoration of spaces with:-
- Implants
- Removable prosthesis (consider types)
- Fixed prosthesis (consider design/types)
Define hyperdontia
More than the normal number of teeth