Part 1 Flashcards

1
Q

Antibiotic associated with: teeth discoloration

A

tetracyclines

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2
Q

Antibiotic associated with: tendonitis

A

fluroquinolones

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3
Q

Antibiotic associated with: red man syndrome

A

vancomycin

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4
Q

Antibiotic associated with: grey baby syndrome

A

chloramphenicol

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5
Q

Antibiotic associated with: cartilage damage in children

A

fluoroquinolones

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6
Q

Antibiotic associated with: nephrotoxicity (esp. when paired with what other drugs?)

A

aminoglycosides with cephalosporins

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7
Q

Antibiotic associated with: ototoxicity (esp. when paired with what other drugs?)

A

aminoglycosides with loop diueretics

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8
Q

Drugs that are assoc. with both ototoxicity and nephrotoxicity?

A

aminoglycosidesvancomycinloop diureticscisplatin

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9
Q

Antibiotic assoc. most with pseudomembranous colitis?

A

ampicillinclindamycin

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10
Q

DOC for gonorrhea

A

ceftriaxone

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11
Q

DOC for Lyme disease or Rocky Mountain spotted fever?

A

tetracyclines

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12
Q

DOC for Giardia lamblia

A

metronidazole

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13
Q

DOC for MRSA and C. difficile colitis

A

vancomycin

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14
Q

Tx for gram(-) rods in renal insufficiency

A

aztreonam

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15
Q

BIG GUN effective in gram(+) cocci, gram(-) rods, anaerobes

A

meropenemimipenem with cilastatin

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16
Q

Prophylaxis in AIDS patients against P. pneumonia

A

TMP-SMXdapsonepentamidine

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17
Q

Solo prophylaxis against TB

A

Isoniazid

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18
Q

Antibiotics safe during pregnancy

A

penicillins, aminopenicillinspiperacillincephalosporinsmacrolides (erythromycin and azithromycin)metronidazole (after 1st trimester)nitrofurantoin

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19
Q

Hesselbach’s Triangle

A

Superior + Lateral = Inferior epigastric artery
Medial = Lateral border of rectus abdominus
Inferior + Lateral = Inguinal ligament

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20
Q

Orotic acid in urine + elevated serum ammonia

A

OTC deficiency

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21
Q

Orotic acid in urine + NO elevations of serum ammonia

A

Orotic aciduria

22
Q

Boy with lip-biting self mutilation, intellectual disability, gout

A

Lesch-Nyhan syndrome

23
Q

Megaloblastic anemia that does not improve with folate and B12

A

Orotic aciduria

24
Q

Major causes of post-op fever:

A

5 W’s

Wind -  Pneumonia
Water - UTI
Wound - wound infection
Walking - DVT
Wonder drugs
25
Q

Macrolide coverage

A

PUS

Pneumonias
URIs (group A strep)
STDs

26
Q

Tetracyclines coverage

A

VACUUM THe BEDRoom

Vibrio cholerae
Acne
Chlamydia
Ureaplasma Urealyticum
Mycoplasma pneumoniae
Tularemia
H. pylori
Borrelia burgdorferi
Rickettsiae rickettsii
27
Q

2nd gen ceph coverage

A
H. flu
Enterobacter
Neisseria
Proteus mirabilis
E. Coli
Klebsiella
Serratia
**also gram(+) cocci
28
Q

Pregnant woman BP drops to BP when supine: Diagnosis?

A

compression of IVC

29
Q

Drugs used reverse neuromuscular blockade with non-depolarizing drugs

A

Cholinesterase inhibitors (neostigmine)

30
Q

Mechanism of action of dantrolene

A

prevents release of calcium from sarcoplasmic reticulum of skeletal muscle

31
Q

What substances inhibit reuptake of norepinephrine?

A

cocaine

TCAs

32
Q

Boot-shaped heart

A

RVH in Tetralogy of Fallot

33
Q

Continuous machine-like murmur

A

PDA

34
Q

Tendon xanthomas seen in

A

Familial hypercholesterolemia

35
Q

Cafe-au-lai spots -

A

NF1, McCune-Albright snydrome

36
Q

Tuft of hair on lower back

A

occult spina bifida

37
Q

Seizures
Intellectual disability
Angiofibroma

A

tuberous sclerosis

38
Q

Most common cause of hypoparathyroidism?

A

thyroidectomy

39
Q

Most common cause of mets to brain?

A

Lung and breast cancer
melanoma
renal cell CC
GI tumor

40
Q

Most common lysosomal disease?

A

Gaucher disease

41
Q

Most common cause of myocarditis?

A

Coxsackievirus, echovirus

42
Q

Amniotic fluid measurement indicative of fetal lung maturity

A

Lecithin to sphingomyelin ratio > 2.0

43
Q

Substance responsible for release of NE from neurons?

A

Calcium

Other substances:
amphetamines
ephedrine
tyramine

44
Q

Which cytokines inhibit Th1 cells?

A

IL-10

45
Q

Aqueous humor pathway

A

Ciliary body –> posterior chamber –> iris and lens angle –> anterior chamber –> reabsorbed in canal of Schlemm

46
Q

MOA of metoclopramide

A

D2 receptor antagonist

5-HT agonist

47
Q

Pudendal block landmark

A

Ischial spine

48
Q

RLE of carbohydrate digestion

A

oligosaccharide hydrolases

found in intestinal brush border

49
Q

What vitamin deficiency results from Hartnup disease?

A

Niacin

Tryptophan deficiency yield Niacin deficiency

50
Q

Dantrolene used for:

A

Neuroleptic malignant syndrome

Malignant hyperthermia