Part 1 Flashcards
Antibiotic associated with: teeth discoloration
tetracyclines
Antibiotic associated with: tendonitis
fluroquinolones
Antibiotic associated with: red man syndrome
vancomycin
Antibiotic associated with: grey baby syndrome
chloramphenicol
Antibiotic associated with: cartilage damage in children
fluoroquinolones
Antibiotic associated with: nephrotoxicity (esp. when paired with what other drugs?)
aminoglycosides with cephalosporins
Antibiotic associated with: ototoxicity (esp. when paired with what other drugs?)
aminoglycosides with loop diueretics
Drugs that are assoc. with both ototoxicity and nephrotoxicity?
aminoglycosidesvancomycinloop diureticscisplatin
Antibiotic assoc. most with pseudomembranous colitis?
ampicillinclindamycin
DOC for gonorrhea
ceftriaxone
DOC for Lyme disease or Rocky Mountain spotted fever?
tetracyclines
DOC for Giardia lamblia
metronidazole
DOC for MRSA and C. difficile colitis
vancomycin
Tx for gram(-) rods in renal insufficiency
aztreonam
BIG GUN effective in gram(+) cocci, gram(-) rods, anaerobes
meropenemimipenem with cilastatin
Prophylaxis in AIDS patients against P. pneumonia
TMP-SMXdapsonepentamidine
Solo prophylaxis against TB
Isoniazid
Antibiotics safe during pregnancy
penicillins, aminopenicillinspiperacillincephalosporinsmacrolides (erythromycin and azithromycin)metronidazole (after 1st trimester)nitrofurantoin
Hesselbach’s Triangle
Superior + Lateral = Inferior epigastric artery
Medial = Lateral border of rectus abdominus
Inferior + Lateral = Inguinal ligament
Orotic acid in urine + elevated serum ammonia
OTC deficiency
Orotic acid in urine + NO elevations of serum ammonia
Orotic aciduria
Boy with lip-biting self mutilation, intellectual disability, gout
Lesch-Nyhan syndrome
Megaloblastic anemia that does not improve with folate and B12
Orotic aciduria
Major causes of post-op fever:
5 W’s
Wind - Pneumonia Water - UTI Wound - wound infection Walking - DVT Wonder drugs
Macrolide coverage
PUS
Pneumonias
URIs (group A strep)
STDs
Tetracyclines coverage
VACUUM THe BEDRoom
Vibrio cholerae Acne Chlamydia Ureaplasma Urealyticum Mycoplasma pneumoniae Tularemia H. pylori Borrelia burgdorferi Rickettsiae rickettsii
2nd gen ceph coverage
H. flu Enterobacter Neisseria Proteus mirabilis E. Coli Klebsiella Serratia **also gram(+) cocci
Pregnant woman BP drops to BP when supine: Diagnosis?
compression of IVC
Drugs used reverse neuromuscular blockade with non-depolarizing drugs
Cholinesterase inhibitors (neostigmine)
Mechanism of action of dantrolene
prevents release of calcium from sarcoplasmic reticulum of skeletal muscle
What substances inhibit reuptake of norepinephrine?
cocaine
TCAs
Boot-shaped heart
RVH in Tetralogy of Fallot
Continuous machine-like murmur
PDA
Tendon xanthomas seen in
Familial hypercholesterolemia
Cafe-au-lai spots -
NF1, McCune-Albright snydrome
Tuft of hair on lower back
occult spina bifida
Seizures
Intellectual disability
Angiofibroma
tuberous sclerosis
Most common cause of hypoparathyroidism?
thyroidectomy
Most common cause of mets to brain?
Lung and breast cancer
melanoma
renal cell CC
GI tumor
Most common lysosomal disease?
Gaucher disease
Most common cause of myocarditis?
Coxsackievirus, echovirus
Amniotic fluid measurement indicative of fetal lung maturity
Lecithin to sphingomyelin ratio > 2.0
Substance responsible for release of NE from neurons?
Calcium
Other substances:
amphetamines
ephedrine
tyramine
Which cytokines inhibit Th1 cells?
IL-10
Aqueous humor pathway
Ciliary body –> posterior chamber –> iris and lens angle –> anterior chamber –> reabsorbed in canal of Schlemm
MOA of metoclopramide
D2 receptor antagonist
5-HT agonist
Pudendal block landmark
Ischial spine
RLE of carbohydrate digestion
oligosaccharide hydrolases
found in intestinal brush border
What vitamin deficiency results from Hartnup disease?
Niacin
Tryptophan deficiency yield Niacin deficiency
Dantrolene used for:
Neuroleptic malignant syndrome
Malignant hyperthermia