PAROMONICINA Flashcards

1
Q

MECANISMO DE ACCIÓN

A

-se une a la sub unidad 30s del ribosoma de los parásitos y bacterias inhibiendo la síntesis de proteínas y causando su muerte

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2
Q

USOS TERAPÉUTICOS

A

-amebiasis intestinal (entamoeba histolytica) fase luminal
-leishmaniasis visceral
-criptospordioses (VIH)
-enterobacterias

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3
Q

EFECTOS ADVERSOS

A

-náuseas vómito dolor abdominal
- diarrea leve
-ototoxicidad
-nefrotoxicidad

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4
Q

CONTRAINDICACIONES

A

-hipersensibilidad aminoglucosidos
-insuficiencia renal grave
-transtornos neuromusculares

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