Parkinsons Disease Medications Flashcards

1
Q

What is the primary action of Levodopa?

A

Levodopa is converted to dopamine in the brain, helping to alleviate symptoms of Parkinson’s disease.

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2
Q

True or False: Carbidopa is often combined with Levodopa to prevent Levodopa from converting to dopamine outside the brain.

A

True

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3
Q

What is the generic name of Sinemet?

A

Levodopa/Carbidopa

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4
Q

What are the main indications for using Dopamine Agonists?

A

Dopamine Agonists are indicated for the treatment of Parkinson’s disease and Restless Legs Syndrome.

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5
Q

What is the action of Pramipexole?

A

Pramipexole stimulates dopamine receptors in the brain.

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6
Q

Fill in the blank: The primary contraindication for using MAO-B inhibitors is ______.

A

concomitant use of certain antidepressants

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7
Q

What are common adverse effects of Levodopa?

A

Common adverse effects include nausea, dizziness, and dyskinesia.

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8
Q

What is the generic name for Mirapex?

A

Pramipexole

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9
Q

True or False: Entacapone is used to enhance the effectiveness of Levodopa.

A

True

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10
Q

What is the primary action of COMT inhibitors?

A

COMT inhibitors prolong the effect of Levodopa by blocking its breakdown.

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11
Q

What is the contraindication for using Ropinirole?

A

Hypersensitivity to the drug or its components.

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12
Q

Which medication is a non-ergot dopamine agonist?

A

Ropinirole

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13
Q

What is the primary role of Anticholinergic drugs in Parkinson’s treatment?

A

They are used to control tremors and rigidity.

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14
Q

Fill in the blank: The generic name for Artane is ______.

A

Trihexyphenidyl

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15
Q

What is a major adverse effect of Anticholinergic medications?

A

Dry mouth

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16
Q

What is the action of Selegiline?

A

Selegiline inhibits the enzyme monoamine oxidase B, leading to increased dopamine levels.

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17
Q

True or False: Amantadine is an antiviral medication that can also help with Parkinson’s symptoms.

18
Q

What is the primary indication for using Amantadine?

A

To treat motor symptoms in Parkinson’s disease.

19
Q

What are common side effects of Amantadine?

A

Common side effects include confusion, dizziness, and insomnia.

20
Q

What is the generic name for Eldepryl?

A

Selegiline

21
Q

Fill in the blank: The primary contraindication for using Rasagiline is ______.

A

concomitant use of certain antidepressants

22
Q

What is the action of Rasagiline?

A

Rasagiline inhibits monoamine oxidase B, increasing dopamine availability.

23
Q

True or False: Levodopa is the first-line treatment for early-stage Parkinson’s disease.

24
Q

What is the primary use of Benztropine?

A

To manage tremors and rigidity in Parkinson’s disease.

25
What class of medication does Pramipexole belong to?
Dopamine Agonists
26
What is the adverse effect associated with prolonged use of Levodopa?
Dyskinesia
27
Fill in the blank: The combination of Levodopa and Carbidopa is marketed under the brand name ______.
Sinemet
28
What is a common risk of using dopamine agonists?
Impulse control disorders
29
What is the action of Entacapone?
Entacapone inhibits catechol-O-methyltransferase, prolonging the action of Levodopa.
30
True or False: Parkinson's disease medications can lead to orthostatic hypotension.
True
31
What are the indications for using Carbidopa/Levodopa?
To treat the symptoms of Parkinson's disease.
32
What is the generic name for Comtan?
Entacapone
33
Fill in the blank: Tardive dyskinesia is a potential adverse effect of ______.
long-term dopamine antagonist use
34
What is the action of dopamine receptor agonists?
They mimic the action of dopamine in the brain.
35
What is a potential contraindication for using Selegiline?
Concomitant use of meperidine.
36
True or False: All Parkinson's disease medications have the same side effects.
False
37
What is a common treatment strategy for advanced Parkinson's disease?
Combination therapy with Levodopa and other medications.
38
What is the action of Amantadine in Parkinson's treatment?
It increases dopamine release and blocks its reuptake.
39
Fill in the blank: The adverse effect of ______ is most commonly associated with dopamine agonists.
nausea
40
What is the role of MAO-B inhibitors in Parkinson's disease?
They help to increase and prolong the action of dopamine.
41
What is the generic name for Requip?
Ropinirole