Parenteral Nutrition: Initiation and Management Flashcards

1
Q

What are the 7 indications for PN?

A
  1. Patients severely malnourished (unable to take oral products for > 7 days OR enteral products)
  2. Severe pancreatitis
  3. Small or large bowel obstruction
  4. Pregnant (severe N/V)
  5. Head injury patients who have no enteral access or GI dysfunction
  6. Severe inflammatory bowel disease exacerbated by oral or enteral nutrition
  7. Extensive bowel surgery causing malabsoprtion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Give two examples of severe inflammatory bowel disease?

A
  • Chron’s disease

- Ulcerative colitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Give an example of an extensive bowel surgery?

A

Short bowel syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How is IBW for females calculated?

A

IBW = 45.5 + 2.3 (height (in) - 60)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How is IBW for males calculated?

A

IBW = 50 + 2.3 (height (in) -60)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

(T/F) - Obesity is considered 130% above IBW

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

(T/F) - Severely malnourished is considered less than 80%

A

FALSE - less than 70%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

(T/F) - In PN, you will use Adj. BW when a patient is obese to solve calculations

A

FALSE - IBW will be used even if the patient is obese

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

(T/F) - In PN, you will use Act. BW when a patient is malnourished to solve calculations

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How is Adj. BW calculated?

A

Adj. BW = IBW + 0.25(Act. BW - IBW)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How is the body mass index (BMI) calculated?

A

BMI = weight (kg) / height (m^2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the range of an overweight BMI - also known as Grade I obesity?

A

25 - 29.9 kg/m^2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

(T/F) - The normal weight BMI is 20 - 24.9 kg/m^2

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the range for a Grade II obese BMI?

A

30 - 40 kg/m^2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

(T/F) - The Grade III obese scale is > 40 kg/m^2

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

For obese patients, what is their goal for kcal/kg?

A

22 kcal/kg of their IBW

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

For obese patients, what is their protein gm/kg goal?

A

2 gm/kg of their IBW

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are the fluid requirements for adults with normal renal function?

A

2500 - 3500 mL/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are the fluid requirements for adults with insufficient renal function?

A

500 - 1500 mL/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What type of insulin can be added to PN bags to control glucose levels?

A

Regular insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the initial dose of insulin?

A

0.1 units/gm of dextrose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

(T/F) - Insulin is usually added to PN bags to prevent hyperglycemia and reduce cost for patient

A

FALSE - it’s not added usually because of the risk of hypoglycemia and a high cost

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

How much should IV fat consist of in total calories?

A

1 - 4%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Why is IVFE (IV fat emulsion) given to nearly all patient?

A

To prevent essential fatty acid deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What are the two main essential fatty acids? Are they produced within the body or need to be given from the environment?

A
  • Linolenic acid and Alpha-linolenic acid

- They are given from the environment (food)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

How should IVFE preparations be given? What filter size should be used?

A
  • In-line IV filter

- A 1.2 micrometer filter size

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

(T/F) - Lipids cannot be given as a separate peripheral IV infusion (piggyback)

A

FALSE - Lipids can be given as a piggyback and MUST not exceed 12 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Are there any contraindications for IVFE?

A

Yes, egg allergy patients - IVFE are stabalized with egg phospholipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What is propofol?

A

A sedative agent that is manufactured as a 10% lipid emulsion

30
Q

(T/F) - Propofol does not require to measure the kcal if administered in a patient who is malnourished

A

FALSE - it needs to be taken into account since it contains lipids in its formulation

31
Q

At what concentration does dextrose have to be in order for total nutrition admixtures (TNAs) to be stable?

A

> 10% of the final concentration

32
Q

At what concentration does amino acids have to be in order for TNAs to be stable?

A

> 4% of the final concentration

33
Q

At what concentration do lipids have to be in order for TNAs to be stable?

A

> 2% of the final concentration

34
Q

(T/F) - Sodium can be given in a PN when it’s clinically needed (use clinical judgement)

A

TRUE

35
Q

In which patients should sodium be avoided in? (3 types)

A
  • Iatrogenic fluid overload
  • End-stage liver disease
  • Congestive heart failure
36
Q

In which patients should sodium be given to? (4 types)

A
  • High ileostomy output
  • High pancreatic fitula output
  • Large nasogastric fluid output
  • Large small bowel losses
37
Q

Sodium content in PN should not exceed how much?

A

154 mEq/L

38
Q

(T/F) - Potassium cannot be given in a PN, even if a patient needs it

A

FALSE - It can be given in a PN but clinicians need to use their clinical judgement

39
Q

(T/F) - Potassium is generally influenced by acid-base status

A

TRUE

40
Q

What happens to potassium serum levels when a patient is metabolic acidic? Does it increase or decrease?

A

Increase (hyperkalemia)

41
Q

What happens to potassium serum levels when a patient is metabolic alkalotic? Does it increase or decrease?

A

Decrease (hypokalemia)

42
Q

What is the recommended parenteral daily intake of calcium?

A

10 mEq OR 200 mg/day

43
Q

In which patients should low amounts of calcium be given? (3 types)

A
  • Hyperparathyroidism
  • Hypophosphatemia
  • Metastatic cancer
44
Q

How do you calculate corrected Ca 2+?

A

Corrected Ca 2+ = measured calcium + 0.8(4 - albumin)

45
Q

What is the recommended parenteral daily intake of magnesium?

A

10 mEq OR 120 mg/day

46
Q

The amount of calcium and magnesium should not exceed what number in a 3-in-1 formulation?

A

20 mEq/L

47
Q

Which disease states require a larger dose of magnesium? (2 types)

A
  • Short bowel syndrome

- Alcoholism

48
Q

What is the recommended parenteral daily intake of phosphorus?

A

30 mmol OR 100 mg/day

49
Q

(T/F) - Omission of PN can induce life-threatening hypophosphatemia within a week in normal renal function patients

A

TRUE

50
Q

What disease states are associated with hypophosphatemia? (4 types)

A
  • Alcohol abuse
  • Thermal injury
  • Refeeding syndrome
  • Trauma
51
Q

If a patient has metabolic acidosis, which salts would you use?

A

Acetate salts

52
Q

If a patient has metabolic alkalosis, which salts would you use?

A

Chloride salts

53
Q

(T/F) - ONLY sodium bicarbonate should not be used in PN formulas

A

FALSE - sodium bicarbonate AND calcium chloride should not be used in PN formulas

54
Q

There are 5 trace elements that can be added once a day – what are the names?

A
  • Zinc
  • Chromium
  • Selenium
  • Manganese
  • Copper
55
Q

What should be done with the trace elements in patients with small/large bowel fluid loses?

A

Provide a zinc supplement of 5-10 mg/day (if needed) with the Trace element cocktail

56
Q

What should be withheld in patients with hepatic cholestasis? Why?

A
  • Copper and Manganese

- Excreted through bile

57
Q

(T/F) - Not every PN should contain MVI

A

FALSE - every PN should contain MVI

58
Q

How many products are available in the US that contain MVI? What are the names?

A
  • 2 products

- MVI-Adult and Infuvite Adult

59
Q

Should iron be added to the TNA formulation? Why or why not?

A

No, it’s not generally stable in TNAs

60
Q

What is preferable, PNs given in central lines or peripheral lines?

A

In central lines, unless the formulated product is needed to be given peripherally

61
Q

Name 4 types of central lines

A
  • PICC
  • Hickman
  • Port-A-Cath
  • Lines in which the tip of the catheter is positioned in the superior vena cava
62
Q

How can you minimize vein damage from administering hypertonic solutions?

A

By administering PN through a large diameter central vein

63
Q

Why is administering PN through a large-diameter central vein going to help minimize vein damage? (2 reasons)

A

Because of rapid blood flow and PN will be diluted quickly

64
Q

If PN is given peripherally, would the solution be hypertonic or less hypertonic?

A

Less hypertonic

65
Q

What must the osmolality be for PPN (peripheral parenteral nutrition)?

A

700 - 900 mOsmol/L

66
Q

Is PPN given for short-term or long-term?

A

Short-term

67
Q

What are some limitations of PPN? (2 limitations)

A
  • Limits concentrations of nutrients (osmolality)

- Fluid overload is possible

68
Q

In which patients is PPN not recommended to? (3 types)

A
  • Long-term PN
  • Fluid restriction
  • Severe under nutrition
69
Q

What should be checked in a patient before discontinuing PN?

A

Make sure patient is consuming 50% or more of an oral diet that contains at least 60 gm of protetin/day

70
Q

(T/F) - Abruptly discontinuing PN is recommended in several patients

A

FALSE - It is not recommended in any patient because it could cause a rebound hypoglycemia

71
Q

How will a patient be discontinued PN if they’re not receiving continuous enteral feedings? (2 steps)

A
  • Decrease 50% of PN rate q 2 hours

- If PN is < 25 mL/hr, discontinue PN