Parenteral fluid therapy Flashcards
body water accounts for what percentage of weight
60% of body weight
of total body water, how much is intracellular and how much is extracellular
- ICF: 2/3
- ECF: 1/3
- ex: TBW = 40 L
- ICF = 25L ; ECF = 15L
- ex: TBW = 40 L
Of the ECF, how much is in interstitial and how much is in plasma
- ECF = 15L
- interstitial = 3/4 = 10L
- plasma = 1/4 = 5L
What are the 3 different types of intravenous fluids
- Crystalloids: solutions that contain sodium
- Colloids: solutions that contain HMW substances that do not migrate easily across capillary walls
- Blood and blood products
What are the different types of Crystalloids
- Isotonic Crystalloids: same salt concentration as normal cells of body and blood
- Hypertonic Crystalloids: higher salt concentration than normal cells of body and blood
- Hypotonic Crystalloids: lower salt concentration than normal cells of body and blood
- other: D5W
What are the two types of Isotonic Crystalloids
- Normal saline: 0.9% NaCl/NS
- Lactated Ringer solution: contain lactate, K+, and Ca2+ in addition to NaCl
When are Isotonic Crystalloids used
- tx of dehydration/hypovolemia
- IV boluses
What is the only Hypertonic Crystalloids
- 3% NS
When is the Hypertonic Crystalloid 3% NS indicated
- life-threatening hyponatremia with significant water excess
Overly rapid correction of hyponatermia with 3% NS could lead to
- osmotic demyelination - central pontine myelinolysis
List the 2 types of Hypotonic crystalloids
- 0.5 NS (0.45% NaCl)
- 0.25 NS
Hypotonic crystalloids distribute where
throughout the total body water
isotonic crystalloids distribute where
uniformly throughout the ECF space
function of Hypotonic crystalloids
- used for maintenance fluid
- **inadequeate for replacing intravascular volume deficits
- not used for tx of dehydration/hypovolemia
Where does D5W distribute
distribute throughout the total body water
when is D5W (5% dextrose in water) used
- tx hypoglycemia
- use with caution in patients with DM
When are Colloids used
- more likely to expand vascular compartment
- used when crystalloids fail to sustain plasma volume due to low osmotic pressure
What are the most commonly used Colloids
albumin preparations
What are the 3 types of Colloids
- Albumin preparation
- Dextran
- Hydroxyethyl starch
what are the 2 types of albumin preparations
- 5% albumin
- 25% albumin