Parenteral fluid therapy Flashcards
body water accounts for what percentage of weight
60% of body weight
of total body water, how much is intracellular and how much is extracellular
- ICF: 2/3
- ECF: 1/3
- ex: TBW = 40 L
- ICF = 25L ; ECF = 15L
- ex: TBW = 40 L
Of the ECF, how much is in interstitial and how much is in plasma
- ECF = 15L
- interstitial = 3/4 = 10L
- plasma = 1/4 = 5L
What are the 3 different types of intravenous fluids
- Crystalloids: solutions that contain sodium
- Colloids: solutions that contain HMW substances that do not migrate easily across capillary walls
- Blood and blood products
What are the different types of Crystalloids
- Isotonic Crystalloids: same salt concentration as normal cells of body and blood
- Hypertonic Crystalloids: higher salt concentration than normal cells of body and blood
- Hypotonic Crystalloids: lower salt concentration than normal cells of body and blood
- other: D5W
What are the two types of Isotonic Crystalloids
- Normal saline: 0.9% NaCl/NS
- Lactated Ringer solution: contain lactate, K+, and Ca2+ in addition to NaCl
When are Isotonic Crystalloids used
- tx of dehydration/hypovolemia
- IV boluses
What is the only Hypertonic Crystalloids
- 3% NS
When is the Hypertonic Crystalloid 3% NS indicated
- life-threatening hyponatremia with significant water excess
Overly rapid correction of hyponatermia with 3% NS could lead to
- osmotic demyelination - central pontine myelinolysis
List the 2 types of Hypotonic crystalloids
- 0.5 NS (0.45% NaCl)
- 0.25 NS
Hypotonic crystalloids distribute where
throughout the total body water
isotonic crystalloids distribute where
uniformly throughout the ECF space
function of Hypotonic crystalloids
- used for maintenance fluid
- **inadequeate for replacing intravascular volume deficits
- not used for tx of dehydration/hypovolemia
Where does D5W distribute
distribute throughout the total body water
when is D5W (5% dextrose in water) used
- tx hypoglycemia
- use with caution in patients with DM
When are Colloids used
- more likely to expand vascular compartment
- used when crystalloids fail to sustain plasma volume due to low osmotic pressure
What are the most commonly used Colloids
albumin preparations
What are the 3 types of Colloids
- Albumin preparation
- Dextran
- Hydroxyethyl starch
what are the 2 types of albumin preparations
- 5% albumin
- 25% albumin
What are the 2 types of Dextran
- Dextran 40
- Dextran 70
When are albumin preparations used
-
edematous patients to mobilize interstitial fluid into vascular space
- not useful if pt’s serum albumin > 2.5 mg/dL
- liver disease, peritonitis, burns, or surgical patients experiencing third spacing
Function of Dextran
- a synthetic glucose polymer which expands intravascular volume equal to the amount infused
function of Hetastarch
- a glycogen-like synthetic molecule that increases the vascular volume to an amount > or = to the volume infused
- more frequently used intra-operatively
List the 3 types of blood products
- packed red blood cells
- platelets
- fresh frozen plasma
where do packed red blood cells distribute
remain entirely within the vascular space
when are packed red blood cells used
- used with crystalloids to expand intravascular volume
-
blood transfusions
- hemorrhage, severe anemia
- patients must be types and screened/crossed in order to determine blood type and antibodies prior to transfusion
When are platelets given
- used in patients with thrombocytopenia or impaired platelet function to prevent or treat bleeding
when is fresh frozen plasma given
- used to correct major bleeding complications in patients on warfarin and/or with vitamin K deficiency
IVF can be given in what three amounts
- bolus
- maintenance
- replacement
What type of IVF can be used for boluses
- NS and LR: dehydration
- Packed RBC: acute blood loss
how much is given in a bolus
250 mL - 1 L bolus
use cation when given boluses to people with
heart failure
Function of Maintenance IVF
- maintains/accounts for ongoing losses of water and electrolytes under normal physiological conditions via urine, sweat, respirations, and stool
- used when patients are not eating or drinking normally
- goal to provide water and electrolyte balance
what IVF is normally used for Maintenance IVF
- D5/0.5 NS with 20 meq KCl
What is the Kg method for determining maintenance IVF for normal adult patients
- for 1st 10 kg of body weight -> 100 ml/kg/day
- for 2nd 10 kg of body weight -> 50 ml/kg/day
- for weight >20 kg -> 20 ml/kg/day
- divide the total of the above by 24 hours to determine hourly rate of infusion
What is the Kg method for determining maintenance IVF for pediatric patients
- weight < 10 kg -> 100 ml/kg
- weight > 10 kg to 20 Kg -> 1000 ml for 1st 10 kg + 50 ml/kg for weight over 10 kg
- weight > 20 kg to 80 kg -> 1500 ml for 1st 20 kg + 20 ml/kg for weight over 20 kg
- divide total of the above by 24 hrs
- *use 0.25 NS
can a bolus containing potassium be given
NO
What is the function of Replacement IVF
- corrects any existing water and electrolyte deficits caused by GI, urinary, skin, or blood losses of “third spacing”
- monitor vital signs, urine output and clinical picture
caution must be exercised when given replacement IVF to patients who are hypo or hypernatremic due to
could lead to osmotic demyelination - central pontine myelinolysis
in addition to maintenance fluids, surgical patients need replacement of fluids lost from
- urine output
- blood loss
- “third spacing”
What is the Parkland formula
- total fluid required during first 24 hours in burn victims
- (percentage of 2nd and 3rd degree burns ) x (body weight in kg) x 4 mL
what type of IVF is given to burn patient s
LR
what is the rule of nines
- each arm = 9%
- head = 9%
- anterior and posterior trunk each = 18%
- each leg = 18%
- perineum = 1 %
What are the two types of parenteral nutrition
- total parenteral nutrition (TPN)
- peripheral parenteral nutrition (PPN)
when is total parenteral nutrition (TPN) indicated
- small bowel resection or complete bowel resection
- inflammatory bowel disease
- anticipated or actual inadequate energy intake by mouth
- significant multisystem disease
route of entry of total parenteral nutrition (TPN)
- requires central venous access via SVC
- most common type of parenteral access
- parenteral nutrition support is expected to be long-term (>7 days)
route of entry for PPN
- requires peripheral venous access
- parenteral nutrition support is expected to be short term (< 7 days)
What should be monitored when patient is on TPN
- intake and output
- daily weights
- labs
- electrolytes, BUN, creatinine, glucose, calcium, magnesium, phosphorous, LFT, triglycerides
complications of total parenteral nutrition (TPN)
- catheter related
- air embolism
- pneumothorax
- DVT
- catheter infecion
- thrombophlebitis