Parcial 1 Flashcards

1
Q

Nociceptores

A

Fibras sensoriales que son las terminaciones periféricas de fibras aferentes sensoriales primarias

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2
Q

Tipos de nocireceptores

A

Cutaneos
Musculo-articúlares
Viscerales

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3
Q

Noxas

A

Estímulo causante del dolor

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4
Q

Dolor rapido

A

0.1 segundo

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5
Q

Dolor lento

A

Despues de 1 segundo

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6
Q

Dolor

A

Esperiemcia sensorial y emocional desagradable asociada con daño tisular real o potencial

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7
Q

Via principal del dolor

A

Espinotalamica

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8
Q

Vias ascendentes

A

Espinotalamico
Espinoreticular
Espinomesencefalico

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9
Q

Mecanismo de dolor

A

Traduccion
Transmicion
Modulacion (gaba, adenosina)

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10
Q

AINES

A

Analgesicos
Antipireticos
Antiagregantes
Antiinflamatorios

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11
Q

Mecanismo de accion de aines

A

Inhibe Cox2 (dolor y fiebre)

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12
Q

COX 1

A

Enzima citoprotectora fisiologica

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13
Q

COX 2

A

Inducida por la lesion que va a hacer inflamacion

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14
Q

Clasificacion de AINES

A

No acidos y Acidos

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15
Q

No aines (no acidos)

A

Paracetamol y dipirona

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16
Q

AINE acidos

A

Salicilatos (Aspirina)
Acidos propionicos (ibuprofeno, naproxdno, ketoprofeno)
Acidos aceticos (diclofenaco, ketorolaco, indometacina)
Oxicams (meloxicam, piroxicam)

17
Q

Opiodes

A

Analgesicos centrales

18
Q

OPIOIDES DOLOR LEVE

A

Tramadol
Propoxifeno
Codeina
Hidrocodna

19
Q

Opiodes dolor grave

A
Morfina
Fentanilo
Oxicodona
Buprenorfina
Hidromorfona
Metafona
20
Q

Mecanismo de accion opioides

A

Inhibición de la via ascendente y disminuyen la sensación dolorosa
A nivel central del dolor a traves de proteinas g inihibitorios (mo kapa y delta)

21
Q

Agonistas puros opiodes

A

Solo estimulan el receptor mo
Naturales (Morfina, codeina, dextrometorfatp)
Semksintericos (oxicodona, tramadol)

22
Q

Dolor compresivo

A

Corticoides

23
Q

Dolor neuropatico

A

Pregabantina

24
Q

Dolor neuropatico paroxistico/lactante

A

Carbamazepina

25
Q

Dolor neuropatico refractario

A

Topiramato vs anestesico local

26
Q

Dolor crpnico asociado a ansiedad-cirisis de panico

A

Benzodiacepina

27
Q

Dolor óseo

A

Bifisfatos

28
Q

Espasmos musculares-hipo

A

Diazepam