Parathyroid Basics

Question 1

What is the basic patho function of the parathyroid gland

Answer 1

Parathyroid gland secretes produces parathyroid hormone that increases calcium in the blood by sequestering it from bones, increased reuptake from kidneys, and increases calcium absorption from the blood
Calcium binds to calcium sensing receptors
Vitamin D decreasing PTH

Question 2

What is the effect of fibroblast growth factor on PTH

Answer 2

Decreases it

Question 3

What is chronic PTH exposure effect on bones

Answer 3

Increased cells, osteoblast, and osteoclast activity
Increased bone remodeling
In long term exposure cytokines take over osteoclast activation

Question 4

What is calcitonin

Answer 4

A hormone that counteracts PTH
Mainly stops osteoclast activity and increases renal clearance

Question 5

Causes of hypercalcemia

Answer 5

Hyperparathyroidism
Cancer
Vitamin D toxic action
Hyperthyroidism
Prolonged immobilization
Renal failure