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PHARMACOLOGY > Parasympathetic ( Agonists And Antagonists) > Flashcards

Parasympathetic ( Agonists And Antagonists) Flashcards

1
Q

A nonselective muscarinic agonist

A

Pilocarpine

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2
Q

Pilocarpine is used to treat

A

Xerostomia and glaucoma

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3
Q

Ganglionic receptors are selectively blocked by

A

Mecamylamine

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4
Q

NMJ receptors are selectively blocked by

A

Atracurium

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5
Q

Direct Acting cholinergic agonists

A

Acetylcholine
Bethanechol
Carbachol(carbamylcholine)
Pilocarpine
Nicotine

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6
Q

Choline esters include

A

Acetylcholine
Carbachol
Bethanechol

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7
Q

Naturally occurring alkaloids include

A

Nicotine
Pilocarpine

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8
Q

Acetylcholine has dual activity or binds two types of receptors

A

Muscarinic and Nicotinic

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9
Q

Actions of Ach

A

Decrease in heart rate and cardiac output
Decrease in bp
Increase in salivary secretion
Increase in gastric acid secretion
Stimulates intestinal secretions and motility

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10
Q

Bethanechol acts on what receptor

A

Muscarinic receptors

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11
Q

Bethanechol majorly acts on?

A

Smooth musculature of the bladder and GI tract

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12
Q

Carbachol acts on both?

A

Muscarinic and Nicotinic receptors

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13
Q

Adverse effects of pilocarpine

A

Blurred vision
Night blindness
Brow ache
Profuse sweating and salivation

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14
Q

Indirect-acting cholinergic agonists: Anticholinesterase agents(reversible) include:

A

Edrophonium
Physostigmine
Neostigmine
Pyridostigmine
Tacrine, donepezil, rivastigmine, and galantamine.

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15
Q

A prototype short acting AChE inhibitor is

A

Edrophonium

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16
Q

Use of edrophonium

A

Used in the diagnosis of Myasthenia gravis

17
Q

Reactivation of acetylcholinesterase is by the use of

A

Pralidoximine

18
Q

Antimuscarinic agents

A

Atropine
Scopolamine
Aclidinium
Glycopyrrolate
Ipratropium
Tiotropium
Tropicamide
Cyclopentolate
Benztropine
Trihexyphenidyl
Oxybutynin
Darifenacin
Fesoterodine
Solifenacin
Tolterodine
Trospium

19
Q

The most effective drug for motion sickness

A

Scopolamine

20
Q

Non depolarizing(competitive) blockers

A

Curare
Mivacurium
Cisatracurium
Pancuronium
Rocuronium
Vecuronium

21
Q

Depolarizing agents (NMB)

A

Succinylcholine

PHARMACOLOGY (3 decks)

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