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753 - micro > Parasitology Quiz > Flashcards

Parasitology Quiz Flashcards

1
Q

Plasmodium vivax

A

Vector - Anopheles mosquito
Intermediate host - human

Attack younger RBCs
Periodicity - 48 hrs

Blood Smear - enlarged RBCs Trophozoite - ameboid/Vaculated Gametocyte round/pigmented

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2
Q

Plasmodium Ovale

A

Vector - Anopheles mosquito
Intermediate host - human

Attack younger RBCs
Periodicity - 48 hours

Blood Smear - RBCs enlarged/Fimbriated/spiky [infects duffy group]
Trophozoite - compact
Gametocyte - elongated/ovoid

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3
Q

Plasmodium falciparum

A

Vector - Anopheles mosquito

Intermediate host - human

Attack all types of RBCs

Periodicity - 36-48 hrs

Blood smear - RBCs normal
Trophozoite -Ring forms
Gametocyte - banana shape
Laveran’s bib

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4
Q

Plasmodium malariae

A

Vector - Anopheles mosquito

Intermediate host - human

Attack older RBCs

Periodicity - 72 hours

Blood smear - RBC normal
Trophozoite - band/dark pigment
Gametocyte - band
rossette pattern

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5
Q

Malaria Misc.

A

Sporogony sexual reproduction mosquito
Schizogony asexual human
Sporozoites (infective) blood stream - merozoites progeny
Trophozoites ring stage infected RBCs

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6
Q

Babesiosis

A

Disease vector: Ixodes dammini (tick)

Causative agents:
Babesia microti (parasite of rodents)
Babesia gibsoni (parasite of canines)
Babesia bovis (parasite of cattle)

Giemsa-stained blood smear
tetrads or maltese cross in RBCs, no stippling or pigment observed in RBCs

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7
Q

Leishmania donovani

A

visceral leishmaniasis

[Kala-Azar (black fever) or dum dum fever]

Vector: Phlebotomus sandfly

Promastigotes infective

Giemsa-stained blood, bone marrow, tissue biopsy

Amastigote stage diagnostic

Reticuloendothelial cells infected

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8
Q

Leishmania tropica

A

cutaneous leishmaniasis

[Old world leishmaniasis, oriental sore, baghdad or delhi boil]

Vector: Phlebotomus sandfly
Promastigotes infective

Skin lymphoid tissue infected

Giemsa-stained fluid underneath ulcer bed

Amastigotes within monocytes diagnostic

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9
Q

Leishmania braziliensis

A

mucocutaneous leishmaniasis

[American leishmaniasis
]
Vector: Lutzomyia & Psychodopygus sandfly

Reticuloendothelial system infected

Giemsa-stained biopsy of ulcer
Amastigote form diagnostic
Culture of infected material for promastigotes

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10
Q

Trypanosoma gambiense

A

Vector: Glossina tsetse fly
[west african sleeping sickness]
trypomastigotes infective stage

lymphatic system and CNS infected

Giemsa-stained blood, lymph node aspirate, CSF
Trypomastigote stage diagnostic

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11
Q

Trypanosoma rhodesiense

A

Vector: Glossina tsetse fly
[East African sleeping sickness]

Trypomastigotes infective

Lymphatic system and CNS infected

Giemsa-stained blood, lymph node aspirate, CSF
Trypomastigote stage diagnostic

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12
Q

Trypanosoma cruzi

A

Vector: Reduviid bug (kissing or triatomid bug)

[Chagas disease]

Trypomastigotes passed in bug’s feces
Multiple tissues infected (heart, brain, liver, eye)

Giemsa-stained blood slides specimen of choice
Trypomastigote stage diagnostic

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13
Q

Filariasis misc.

A

Blood and tissue nematodes

adult worm/larval - microfilariae

Inhabit peripheral blood, lymphatics, deep tissue

Get blood sample night vs. day

Microfilariae morphology
Presence or absence of sheath around worm
Distribution of nuclei within tip of worm

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14
Q

Wuchereria bancrofti

A

Disease: Elephantiasis

Vector: Culex and Anopheles mosquitoes

Nocturnal periodicity

Giemsa-stained blood smears for microfilariae

Pointed tail without nuclei
Presence of sheath around the ends

Recovery of microfilariae through Nucleopore filter

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15
Q

Brugia malayi

A

Presence of 2 nuclei in tail tip set apart from the rest

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16
Q

Loa loa

A

Disease: Loiasis
African eye worm infection

Vector: Chrysops deerfly

Invasion: Blood and subcutaneous tissues

Diurnal periodicity – sample needs to be collected in the day time

Giemsa-stained blood smears for microfilariae
Tail with continuous row of nuclei

17
Q

Onchocerca volvulus

A

Disease: river blindness

Vector: Simulium blackfly

Invasion: subcutaneous tissue, skin, eye

Giemsa-stained tissue (skin snips) smears NOT IN BLOOD
Continuous row of nuclei in tail but not in the tip

Recovery of worm from infected nodules

No periodicity observed

18
Q

Toxoplasmosis

A

Causative Agent: toxoplasma gondii

disease of blood and lymphatic vessels

Serology
IgG - infected at sometime, IgM infected over 2 years ago
+ infected w/in last 3-6 months

19
Q

Lyme Disease

A

Borrelia burgdorferi
Vector: Ixodes dammini (tick)

Bull’s eye rash - heart problems - joint damage

Serology, culture, tissue microscopy (silver stain)
EIA - sonicated b. burgdorferi, purified flagellin protein, C6 peptide

753 - micro (5 decks)

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