Parasitology: Protazoa Flashcards

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1
Q

What are the different types of protozoa?

A
  • Amoebas
  • Flagellates
  • Cilliates
  • Apicomplexia
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2
Q

Describe amoebas life-cycle.

A

Cyst (round, immotile, infective, protected by resistant wall, passed in stool) –> Trophozoite (motile, multiple hosts)

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3
Q

Describe characteristics found in Trphozoites.

A
  • Karysome = with centered or off-centered nucleus
  • Peripheral chromatin = surrounds karysome
  • If RBC are seen in cytoplasm = enteramoeba histolytica
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4
Q

Describe characteristics found in cysts.

A

-Chromatoid bar = rod-shaped structure in cytoplasm that has RNA material

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5
Q

What are the amoebas that were talked about in class?

A
  • Acanthamoeba

- Naegleria fowleri

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6
Q

Acanthamoeba details

A
  • Opportunistic infection
  • Found in contaminated soil/water… Brackish water
  • Encephalitis + keratitis in immunocompromised
  • Taking Trphozoites of cysts from brain = diagnostic
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7
Q

Naegleria fowleri details

A
  • Inhaled fresh, warm, water –> olfactory nerve –> brain = meningoencephalitis (fatal)
  • Taking Trphozoites of cysts from brain = diagnostic
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8
Q

What are the different flagellates?

A
  • Giardia lamblia
  • Trichomonas Vaginalis
  • Trypanosoma
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9
Q

Giardia lamblia details.

A
  • Common in US (camping)
  • Infects duodenum –> Diarrhea
  • Flatulence, water/greasy/foul smelling poop
  • “Old professor” has sucking disks + median bodies
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10
Q

Trichomonas Vaginalis details

A

-Vaginitis: Frothy, green, foul-smelling discharge

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11
Q

What are the different types of Trypanosoma?

A
  • T. brucci rhodesiense + T. gambiense
  • T. cruzi
  • Leishmania
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12
Q

T. brucci rhodesiense + T. gambiense details

A

-Tsetsy fly –> African sleeping sickness

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13
Q

T. cruzi details

A
  • Latin America –> Kissing bug –> Chagas

- C shaped, undulating membrane and flagella

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14
Q

Leishmania details

A
  • Sand fly

- Promastigote turns into –> Amastigotes

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15
Q

What are the cilliates?

A

-Balantidum Coli

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16
Q

What are the apicomplexia?

A
  • Cryptosporidium
  • Cyclospora cayetanensis
  • Plasmodium
17
Q

Cryptosporidium details

A
  • More severe in immunocompromised

- Oocytes have 4 sporozoites and 1-6 granules

18
Q

Cyclospora cayetanensis details

A
  • More severe in immunocompromised

- Oocytes are BIGGER than Cryptosporidium’s

19
Q

What are the different types of Plasmodium?

A
  • P. vivax
  • P. ovale
  • P. malariae
  • P. falciparum
20
Q

Describe the transmission of malaria.

A

1) Mosquito ingests gametocyte and they develop into –> sporozites
2) Mosquito bites human
3) Sporozites enter liver cells
4) Sporozites develop into –> merozoites and they enter the bloodstream
* In RBS you get the following*
5) Trophozoite (ring form)
6) Schizont
7) Ruptured RBC with merozites
8) Gametocytes
9) Mosquito bites infected indiv and cycle starts all over again

21
Q

Which is the worst plasmodium to get?

A
  • P. falciparum
  • Has a banana shaped gametocyte
  • Causes organ damage + neuro system manifestations