PARASITOLOGY Flashcards

1
Q
  1. Enterobius vermicularis infection is usually
    diagnosed by finding
    A. Eggs in perianal specimens
    B. Larvae in perianal specimens
    C. Larvae in feces
    D. Eggs in the feces
A

A. Eggs in perianal specimens

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2
Q
  1. The best direct diagnosis of Echinococcus granulosus
    infection in humans is made by identification of
    A. Adult worms in the intestine
    B. Adult worms in tissues
    C. Eggs in feces
    D. Hydatid cysts in tissues
A

D. Hydatid cysts in tissues

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3
Q
  1. Which statement is correct for specimen collection and processing?
    A. Stool samples can contain urine.
    B. Stools can be frozen without affecting parasitic
    structure.
    C. Liquid stools are best for detecting ameba and
    flagellate trophozoites.
    D. Unpreserved stools can remain at room
    temperature for up to 72 hours.
A

C. Liquid stools are best for detecting ameba and
flagellate trophozoites.

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4
Q
  1. Cysts are the infective stage of this intestinal flagellate.
    A. Balantidium coli
    B. Dientamoeba fragilis
    C. Entamoeba coli
    D. Giardia lamblia
A

D. Giardia lamblia

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5
Q
  1. Eggs or larvae recovered in the stool are not routinely
    used to diagnose infections caused by which one of
    the following helminths?
    A. Trichinella spiralis
    B. Strongyloides stercoralis
    C. Necator americanus
    D. Ascaris lumbricoides
A

A. Trichinella spiralis

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6
Q
  1. Many parasites have different stages of growth within
    different hosts. The host where the sexual
    reproductive stage of the parasites exists is called the
    A. Commensal
    B. Definitive host
    C. Intermediate host
    D. Vector
A

B. Definitive host

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7
Q
  1. Species identification of an immature amebic cyst can be very difficult. The presence of a large glycogen
    mass is sometimes seen in
    A. Dientamoeba fragilis
    B. Endolimax nana
    C. Entamoeba coli
    D. Entamoeba histolytica
A

C. Entamoeba coli

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8
Q
  1. Which of the following is typical in cysts of lodamoeba butschlii?

A. A glycogen mass
B. Blunt chromatoidal bars
C. Four nuclei with large karyosomes
D. Many ingested bacteria

A

A. A glycogen mass

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9
Q
  1. Which of the following is the most important feature
    in differentiating cysts of Entamoeba histolytica from
    E. dispar?
    A. Number of nuclei
    B. Size of the cyst
    C. Shape of the karyosome
    D. Distinguishing surface antigens by
    immunologic assays
A

D. Distinguishing surface antigens by
immunologic assays

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10
Q
  1. Which of the following findings in a peripheral blood
    smear is especially associated with tissue-invading
    helminths but may also be found in a variety of
    allergic conditions and other diseases?
    A. Eosinophilia
    B. Leukopenia
    C. Lymphocytosis
    D. Neutropenia
A

A. Eosinophilia

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11
Q
  1. A 48-year-old man from Texas developed fever and
    weakness 16 days after a hunting trip in northwest
    Tanzania. Several days after the onset of fever, he
    noticed a raised, tender, erythematous nodule (6-8 cm
    in diameter) on the posterior aspect of his right arm.
    He was hospitalized in Africa and treated for 5 days
    with a cephalosporin for presumed cellulitis. After
    little improvement, he returned to Texas. On arrival,
    the patient had a temperature of 38.9°C (102°F), a
    morbilliform rash of the trunk, and right- sided,
    anterior cervical lymphadenopathy. Cerebrospinal
    fluid contained 12 red cells and 18 mononuclear
    cells/uL and a normal protein level (32 mg/dL).
    Laboratory tests of peripheral blood revealed a
    hemoglobin level of 107 g/L, a white cell count of 2.4
    X 109/L, and a platelet count of 75 X 109/L. The
    diagnosis was made by finding the extracellular
    flagellate parasite in a peripheral blood smear. Which
    of the following is the most probable etiologic agent
    of this infection?
    A. Leishmania donovani
    B. Trypanosoma brucei
    C. Trypanosoma cruzi
    D. Toxoplasma gondi
A

B. Trypanosoma brucei

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11
Q
  1. Which species of malaria parasite usually has
    ameboid trophozoites and produces small reddish
    dots in the red blood cell cytoplasm?
    A. Plasmodium knowlesi
    B. Plasmodium falciparum
    C. Plasmodium malariae
    D. Plasmodium vivax
A

D. Plasmodium vivax

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12
Q
  1. Which of the following is a mercury- containing
    fixative used to preserve parasites in stool specimens?
    A. Formalin
    B. Sodium acetate
    C. Buffered glycerol
    D. Polyvinyl alcohol
A

D. Polyvinyl alcohol

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12
Q
  1. With a fecal specimen, which one of the following is
    the most dependable procedure for the accurate,
    specific diagnosis of an intestinal amebic infection?
    A. Direct saline wet mount
    B. Direct iodine wet mount
    C. Permanently stained smear
    D. Formalin - ethyl acetate sedimentation technique
A

C. Permanently stained smear

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12
Q
  1. In an examination of stained blood films, Babesia spp.
    are likely to resemble
    A. Leishmania donovani
    B. Plasmodium falciparum
    C. Toxoplasma gondii
    D. Trypanosoma cruz
A

B. Plasmodium falciparum

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12
Q
  1. Examination of a fecal smear following acid-fast stain
    reveals round acid-fast positive structures 8-10 um in
    diameter. You should suspect
    A. Cryptosporidium
    B. Cyclospora
    C. Isospora
    D. Microsporidia
A

B. Cyclospora

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12
Q
  1. A 22-year-old male presents to his family physician complaining of fatigue, muscle pain, periorbital edema, and fever. He denies travel outside the U.S. The physician suspects infectious mononucleosis; however, serologic tests for infectious mononucleosis
    are negative. The complete blood count revealed a slightly elevated white blood count, and there were
    10% eosinophils on the differential. Which of the following should be considered part of the differential
    diagnosis?

A. Ascaris lumbricoides
B. Taenia solium
C. Trichinella spiralis
D. Trypanosoma cruzi

A

C. Trichinella spiralis

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12
Q
  1. Which Schistosoma species has a large terminal
    spine?
    A. S. haematobium
    B. S. japonicum
    C. S. mansoni
    D. S. mekongi
A

A. S. haematobium

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12
Q
  1. Elephantiasis is a complication associated with which
    of the following?
    A. Cysticercosis
    B. Guinea worm
    C. Hydatid cyst disease
    D. Filariae
A

D. Filariae

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13
Q
  1. A patient with history of human immuno- deficiency
    virus infection presents with a 5-day history of diarrhea and weight loss. A series of stool specimens
    is collected and examined for the presence of ova and parasites. An acid-fast stain on direct smear reveals pink-stained round structures approximately 4 um in
    diameter. The most likely pathogen is
    A. Blastocystis hominis
    B. Cryptosporidium sp.
    C. Isospora sp.
    D. Microsporidium
A

B. Cryptosporidium sp.

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14
Q
  1. A 55-year-old female presents to her physician
    complaining of a fever that “comes and goes” and fatigue. A complete blood count reveals decreased red
    blood cell count and hemoglobin. History reveals the patient recently traveled through Europe and Africa.
    You should suspect
    A. Cutaneous larval migrans
    B. Filariasis
    C. Malaria
    D. Trichinella
A

C. Malaria

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15
Q
  1. The disease most commonly associated with Acanthamoeba sp. is
    A. Diarrhea
    B. Keratitis
    C. Liver abscess
    D. Meningoencephalitis
A

B. Keratitis

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16
Q
  1. A modified trichrome stain of a fecal smear can be
    used to detect microsporidia. Which of the following
    would describe the appearance of this parasite in this
    stain?
    A. Purple circles, 10-15 um in diameter
    B. Pink ovals, 1-3 um in diameter
    C. Blue ovals, 4-6 um in diameter
    D. Fluorescent circles, 8-12 um in diameter
A

B. Pink ovals, 1-3 um in diameter

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17
Q
  1. Hydatid cysts in humans are due to ingestion of a tapeworm stage normally found in canines. This stage
    is the
    A. Cercaria
    B. Cercocystis
    C. Cysticercus
    D. Embryonated egg
A

D. Embryonated egg

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18
25. Oocysts, the infective stage of Toxoplasma gondii, is found in A. Cat feces B. Human feces C. Undercooked pork D. Undercooked beef
A. Cat feces
19
26. A 15-um pear-shaped flagellate with a visible parabasal body and "falling leaf" motility in a direct saline mount of a diarrheal stool specimen is most probably A. Balantidium coli B. Chilomastix mesnili C. Giardia lamblia D. Trichomonas hominis
C. Giardia lamblia
20
27. This parasitic infection may result in vitamin B12 deficiency, and individuals with pernicious anemia are predisposed to more severe symptoms. A. Diphyllobothrium latum B. Echinococcus granulosus C. Hymenolepis diminuta D. Taenia saginata
A. Diphyllobothrium latum
21
28. Knowledge of nocturnal periodicity is especially important in the diagnosis of certain infections caused by A. Babesia B. Plasmodium C. Microfilariae D. Trypanosoma
C. Microfilariae
22
29. For which of the following diseases is close contact with an infected human host the most important mechanism of transmission? A. Schistosomiasis B. Toxoplasmosis C. Trichinosis D. Trichomoniasis
D. Trichomoniasis
23
30. Which of the following helminths produces an elongate, barrel-shaped egg (50 X 22 um) with a colorless polar plug at each end? A. Ascaris lumbricoides B. Hymenolepis nana C. Necator americanus D. Trichuris trichiura
D. Trichuris trichiura
24
31. Which species of Plasmodium may readily be identified when crescent-shaped gametocytes are found in stained blood films? A. P. falciparum B. P. malariae C. P. ovale D. P. vivax
A. P. falciparum
25
32. Cysts of Giardia lamblia A. Contain four nuclei B. Are motile by flagella C. Have an undulating membrane D. Are rarely found in stool specimens
A. Contain four nuclei
26
33. Migration of larva through the skin can sometimes produce allergic reactions called larva migrans; this is associated with A. Strongyloides stercoralis B. Dracunculus medinensis C. Onchocerca volvulus D. Loa loa
A. Strongyloides stercoralis
27
34. A free-living ameba that causes primary amebic meningoencephalitis is A. Dientamoeba fragilis B. Entamoeba coli C. Entamoeba histolytica D. Naegleria fowleri
D. Naegleria fowleri
28
35. Decontamination of drinking water, fruits, and vegetables before consumption is necessary in countries without well- developed public sanitation. Which of the following diseases would probably be least affected by that kind of precaution? A. Amebiasis B. Ascariasis C. Filariasis D. Giardiasis
C. Filariasis
29
36. Which stage of Taenia saginata is usually infective for humans? A. Cysticercus larva B. Embryonated egg C. Filariform larva D. Rhabditiform larva
A. Cysticercus larva
30
37. This amebic cyst has an average size of 6-8 um and is usually spherical. When mature, it has four nuclei, but immature cysts with one or two nuclei are often seen. The nuclei have fine uniform granules of peripheral chromatin and small, discrete, usually central karyosomes. Chromatoidal bars with bluntly rounded ends are sometimes present. Name the species. A. Endolimax nana B. Entamoeba coli C. Entamoeba hartmanni D. Entamoeba histolytica
C. Entamoeba hartmanni
31
38. Which stage of Trichuris trichiura is infective for humans? A. Proglottid B. Filariform larva C. Rhabditiform larva D. Embryonated ovum
D. Embryonated ovum
32
39. An intestinal parasite is seen in an iodine- stained fecal wet mount that is described as being 25 (Jimin diameter with a homogenously stained central body surrounded by a thin ring of cytoplasm containing a number of nuclei. This best describes A. Blastocystis hominis B. Endolimax nana C. Entamoeba dispar D. lodamoeba butschlii
A. Blastocystis hominis
33
40. Sanitary disposal of human feces is the most important factor in decreasing the incidence of most infections caused by intestinal parasites. Which of the following diseases would not be affected by that kind of sanitation? A. Ascariasis B. Taeniasis C. Trichinosis D. Hookworm infection
C. Trichinosis
34
41. Which species of Plasmodium is characterized by the presence of Schuffner's dots in the infected erythrocytes? A. Plasmodium falciparum B. Plasmodium knowlesi C. Plasmodium malariae D. Plasmodium ovale
D. Plasmodium ovale
35
42. Which of the following is the largest intestinal protozoa infecting humans? A. Balantidium coli B. Dientamoeba fragilis C. Entamoeba histolytica D. Giardia lamblia
A. Balantidium coli
36
43. The rhabditiform larvae of Strongyloides stercoralis A. Mate and produce ova B. Are infective for humans C. Are the diagnostic form found in feces D. Are found in the blood of infected human
C. Are the diagnostic form found in feces
37
44. Which species of Plasmodium can have exoerythrocytic stages capable of causing relapses months or years after initial infection? A. P. falciparum B. P. ovale C. P. malariae D. P. cynomolgi
B. P. ovale
38
45. A Giemsa-stained thick blood film showed many ring forms with no older stages, and a number of the rings had double chromatin dots. These findings are characteristic of A. Plasmodium falciparum B. Plasmodium vivax C. Plasmodium malariae D. Plasmodium ovale
A. Plasmodium falciparum
39
46. Which of the following nematode parasites is acquired from eating inadequately cooked, infected pork? A. Strongyloides stercoralis B. Taenia saginata C. Taenia solium D. Trichinella spiralis
D. Trichinella spiralis
40
47. Which of the following pairs of helminths cannot be reliably differentiated by the appearance of their eggs? A. Ascaris lumbricoides and Necator americanus B. Hymenolepis nana and H. diminuta C. Necator americanus and Ancylostoma duodenale Diphyllobothrium latum and Fasciola hepatica
C. Necator americanus and Ancylostoma duodenale Diphyllobothrium latum and Fasciola hepatica
41
48. Which of the following forms of Toxoplasma gondii are produced in infected humans? A. Bradyzoites B. Macrogametes C. Sporoblast D. Oocysts
A. Bradyzoites
42
49. Hematuria is a typical sign of human infection caused by A. Trypanosoma cruzi B. Trichinella spiralis C. Trichomonas vaginalis D. Schistosoma haematobium
D. Schistosoma haematobium
43
50. Which of the following is the vector for Babesia? A. Fleas B. Lice C. Ticks d. mosquitoes
C. Ticks
44
51. Chagas disease (American trypanosomiasis) is caused by A. Trypanosoma brucei B. Trypanosoma cruzi C. Leishmania braziliense D. Dracunculus medinensis
B. Trypanosoma cruzi
45
52. Which of the following is the preferred anticoagulant for preparing blood smears for diagnosing malaria? A. EDTA B. Heparin C. Sodium citrate D. Sodium fluoride
A. EDTA
46
53. Refer to Color Plate 38*. This is a photomicrograph of a trichrome stain of a fecal smear, magnification400 X. The parasite measures ** 65 X 45 um**. What is the identification of this parasite? A. Balantidium coli B. Diphyllobothrium latum C. Giardia lamblia D. Schistosoma japonicum
A. Balantidium coli
47
54. Refer to Color Plate 39 *. This is a photomicrograph of an iodine wet prep made from a stool sample; magnification is 400X. The ovum is about **70 X 50 um**. What is the identification of the parasite? A. Hookworm B. Enterobius vermicularis C. Trichuris trichiura D. Ascaris lumbricoides
D. Ascaris lumbricoides
48
55. Refer to Color Plate 40 * . This is a photomicrograph of an iron hematoxylin stain from a fecal smear. The magnification is 1000X. The parasite is approximately **20um long and 15 um** wide. What is the identification of this parasite? A. Chilomastix mesnili trophozoite B. Giardia lamblia trophozoite C. Trichomonas hominis trophozoite D. Trichomonas tenax trophozoite
B. Giardia lamblia trophozoite
49
56. Refer to Color Plate 41*. This is a photo- micrograph of an iron hematoxylin stain from a fecal smear. The magnification is 1000X. The parasite is approximately **12 um in diameter.** What is the identification of this parasite? A. Entamoeba histolytica trophozoite B. Entamoeba hartmanni trophozoite C. Dientamoeba fragilis trophozoite D. Entamoeba coli trophozoite
C. Dientamoeba fragilis trophozoite
50
57. Refer to Color Plate 42 *. This is a photo micrograph of an iodine wet-mount from a fecal sample. The magnification is 1000X. The parasite is approximately **25 um in diameter.** What is the identification of this parasite? A. Entamoeba histolytica cyst B. Entamoeba histolytica trophozoite C. Entamoeba coli cyst D. Entamoeba coli trophozoite
C. Entamoeba coli cyst
51
58. Refer to Color Plate 43*. This is a photo- micrograph of an iodine wet mount from a fecal sample. The magnification is 400X. The ovum is approximately **70 X 38 um.** What is the identification of this parasite? A. Hookworm B. Ascaris lumbricoides C. Diphyllobothrium latum D. Taenia solium
A. Hookworm
52
59. Refer to Color Plate 44 * . This is a photomicrograph of a trichrome stain from a fecal smear. The magnification is 1000X. The parasite is approximately **15 (um in diameter. **What is the identification of this parasite? A. Entamoeba hartmanni B. Dientamoeba fragilis C. lodamoeba butschlii D. Blastocystis hominis
D. Blastocystis hominis
53
60. Refer to Color Plate 45 *. This is a photomicrograph of a blood smear stained with Wright's stain. Identify the parasite. A. Babesia sp. B. Plasmodium malariae C. Plasmodium falciparum D. Trypanosoma cruzi
B. Plasmodium malariae