Parasites + Typhoid Flashcards

1
Q

Malaria is associated with which cancer?

A

Burkitt’s lymphoma

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2
Q

Malaria is caused by ______ species and the most severe malaria is caused by _________

A

Plasmodium species

Most severe= P. falciparum

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3
Q

Fever pattern for malaria falciparum is…

A

Quotidian (every day)

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4
Q

Incubation period for P. falciparum

A

7-14 days.

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5
Q

Malaria is transmitted via…

A

Female anopheles mosquito

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6
Q

Symptoms of malaria

A
Fever
Rigor
Headache
Fatigue
GI upset
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7
Q

Features of severe malaria

A
  • Cerebral malaria
  • Acute respiratory distress
  • Blackwater fever
  • Renal failure (nephrotic syndrome)
  • Haemolysis
  • Hypoglycaemia
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8
Q

Signs of malaria

A

Hepato/splenomegaly

Jaundice

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9
Q

Gold standard investigation for malaria

A

Peripheral blood smear

  • Thick and thin film
  • Giemsa staining
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10
Q

Blood tests for malaria

A

FBC

  • Low plt
  • Anaemia

U+Es
- Deranged in renal failure (hyponatraemia, elevated urea/ cr)

LFTs
- Raised enzymes

LDH
- Raised

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11
Q

Management of severe falciparum malaria

A

Artesunate therapy

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12
Q

Management of uncomplicated falciparum malaria

A

Quinine

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13
Q

_______ is given to kill hypnozoites in liver for malaria caused by ______ and _______

A

Primaquine

  • P. vivax
  • P. ovale
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14
Q

Typhoid fever is caused by ______

A

Salmonella thyphi

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15
Q

Salmonella is a Gram_____ ______(shape) bacteria

A

Gram-negative bacillus

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16
Q

Incubation period of typhoid is ______ days

A

10-20 days

17
Q

Typhoid is transmitted via …. route

A

Fecal-oral (contaimined food/water)

18
Q

The endemic region for typhoid is…

A

South-East asia

19
Q

Presentation of typhoid fever in first week [5]

A

Bradycardia, slow rising fever (Faget’s sign)

Headache

Nose bleeds

Drug cough

Abdominal pain

20
Q

Presentation of typhoid fever (Second week)

A

High, swinging fever

Relative bradycardia

Delirium

Rose spots

GI upset

Hepatosplenomegaly

21
Q

Diagnosis of typhoid fever

A

Blood culture

Stool culture

Urine culture

Rose spots culture

Bone marrow culture

22
Q

______ antibiotic is used for suspected thyphoid

A

Azithromycin