Parasites + Typhoid Flashcards
Malaria is associated with which cancer?
Burkitt’s lymphoma
Malaria is caused by ______ species and the most severe malaria is caused by _________
Plasmodium species
Most severe= P. falciparum
Fever pattern for malaria falciparum is…
Quotidian (every day)
Incubation period for P. falciparum
7-14 days.
Malaria is transmitted via…
Female anopheles mosquito
Symptoms of malaria
Fever Rigor Headache Fatigue GI upset
Features of severe malaria
- Cerebral malaria
- Acute respiratory distress
- Blackwater fever
- Renal failure (nephrotic syndrome)
- Haemolysis
- Hypoglycaemia
Signs of malaria
Hepato/splenomegaly
Jaundice
Gold standard investigation for malaria
Peripheral blood smear
- Thick and thin film
- Giemsa staining
Blood tests for malaria
FBC
- Low plt
- Anaemia
U+Es
- Deranged in renal failure (hyponatraemia, elevated urea/ cr)
LFTs
- Raised enzymes
LDH
- Raised
Management of severe falciparum malaria
Artesunate therapy
Management of uncomplicated falciparum malaria
Quinine
_______ is given to kill hypnozoites in liver for malaria caused by ______ and _______
Primaquine
- P. vivax
- P. ovale
Typhoid fever is caused by ______
Salmonella thyphi
Salmonella is a Gram_____ ______(shape) bacteria
Gram-negative bacillus
Incubation period of typhoid is ______ days
10-20 days
Typhoid is transmitted via …. route
Fecal-oral (contaimined food/water)
The endemic region for typhoid is…
South-East asia
Presentation of typhoid fever in first week [5]
Bradycardia, slow rising fever (Faget’s sign)
Headache
Nose bleeds
Drug cough
Abdominal pain
Presentation of typhoid fever (Second week)
High, swinging fever
Relative bradycardia
Delirium
Rose spots
GI upset
Hepatosplenomegaly
Diagnosis of typhoid fever
Blood culture
Stool culture
Urine culture
Rose spots culture
Bone marrow culture
______ antibiotic is used for suspected thyphoid
Azithromycin
