Parasites Flashcards

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1
Q

What are the three different groups of parasites?

A

Protozoa
Helminths
Ectoparasites

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2
Q

Amoeba are protozoan parasites. What is the name of their cytoplasmic protrusions and what are their 2 different forms may occur as?

A

Amoeba have cytoplasmic protrusions called pseudopodia. They may occur as trophozoites which are the active growing forms or as cysts which are environmentally protected forms (like spores)

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3
Q

Entamoeba histolytica is a gut amoeba pathogen. What are the symptoms it causes and how and how is it transmitted?

A

E. histolytica symptoms range from asymptomatic to acute or chronic diarrhea caused by burrowing into the colonic wall causing bleeding. Transmitted by feces, oral, contaminated food/water

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4
Q

Giardia lamblia is a flagellated protozoan parasite that has the same transmission and symptoms as E. histolytica. How is it diagnosed?

A

Microscopy of stool or detection of antigen in stool via EIA

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5
Q

What is the flagellated protozoan parasite responsible for vaginitis? What is the special feature of its life cycle that influences its transmission? How is it detected?

A

Trichomonas vaginalis. It lacks a cyst form and can therefore only be transmitted in the trophozoite form which is very fragile. It is detected by microscopy of discharge for live organisms or with staining for non-viable organisms

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6
Q

Trypanosoma species are responsible for a number of disease. What are the specific species responsible for African sleeping sickness and South American chagas disease? What is the vector for each disease?

A

African: T. brucei, Tse-tse fly

South american: T. cruzi, reduvid bug

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7
Q

What morphological characteristic could you use to distinguish between Trypanosoma brucei and Trypanosoma cruzi?

A

Brucei are more “C” shaped than cruzi

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8
Q

Describe the basic characteristics of the protozoan phylum Apicomplexa and the 3 disease the pathogenic species cause

A

Apicomplexa are obligate intracellular parasites whose mature forms are non-motile. The 3 diseases they cause are malaria, cryptosporidiosis and toxoplasmosis

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9
Q

What is malaria and the organism responsible for the disease? How is it detected?

A

Malaria is episodic fevers and anemia caused by protozoan parasites Plasmodium spp.
Malaria is detected by staining blood samples and looking for parasites

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10
Q

What type of disease does cryptosporidium spp. cause? How is the disease transmitted and detected?

A

Cryptosporidium may cause watery diarrhea. They are transmitted fecal-oral, water or zoonotic. Can be detected by microscopy of stool or antigen detection in stool by EIA

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11
Q

What group of people are most at risk for severe disease from Toxoplasma gondii infection and why? How is the protozoan transmitted and detected?

A

Usually asymptomatic infection but can cause fetal defects during pregnancy. Transmitted by poorly cooked meat or cat stool. Detected by serology

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12
Q

What type of worms are platyhelminthes?

A

Flat worms

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13
Q

What type of flat worm are cestodes? Descibe their morphology

A

Tape worms. They are ribbon-like and segmented. They lack a digestive system and attach to the host gut wall via a scolex

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14
Q

Describe the life cycle of cestodes (tape worms)

A

The gut of the definitive host contains adult worms which lay eggs (ova) that get passed into the environment. An intermediate host will ingest the ova. The ova develop into larvae in the intermediate host tissue. The definitive host ingests the intermediate host and becomes infected with larvae. The larvae develop into the adult form in the host gut.

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15
Q

What are the 2 principle cestode pathogens, the disease they cause, their intermediate hosts and how they’re detected in the definitive host

A

Taenia saeginata (beef) and Taenia solium (pork). They can cause abdominal discomfort in humans. Detected by the presence of ova or adult segments in stool.

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16
Q

Describe the disease cysticercosis, the causal organism and how it is detected

A

Cysticercosis is the distribution of cysts throughout tissues in the body caused by Taenia solium. It is detected by serology or diagnositic imaging (x-ray, ultra sound)

17
Q

Another group of platyhelminthic worms are trematodes, what is another name for them?

A

Flukes

18
Q

Describe the morphology of trematodes

A

Leaf-shaped, hermaphroditic, primitive gut with suckers for attachment.

19
Q

What is the difference between the trematode life cycle and cestode lifecycle?

A

Trematodes have two intermediate hosts (the second IH is eaten by the DH) whereas cestodes have one intermediate host

20
Q

What is the principle trematodal pathogen in humans? What is its intermediate host, disease, transmission and detection?

A

Schistosoma spp. cause schistosomiasis. IH: snails, transmitted by penetration of the skin. Detected by presence of ova in stool

21
Q

What is another name for nematodes?

A

Roundworms

22
Q

Describe the morphology of nematodes. Which one is the principle human pathogen?

A

Round, separate sexes (all the other pathogenic worms we talked about re hermaphrodites), have GI tract
Ascaris lumbricoides is the principle human pathogen

23
Q

What is elephantiasis and what causes the disease?

A

Swelling and deformity of limbs and genitalia caused by filaria roundworms.