Parasites Flashcards

1
Q

What is a parasite

A

An organism that lives on, or in, a host

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2
Q

What is the sole goal of parasites

A

to reproduce and pass on their genes

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3
Q

What is the difference between bacteria and parasites

A

Parasites are much bigger and eukaryotic

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4
Q

What is the definition of a primary host

A

in this host the parasite reaches maturity and will undergo sexual reproduction

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5
Q

What is the definition of intermediate host

A

Host that harbours the parasite for a short transition period during which development occurs. Asexual reproduction may occur but sexual reproduction will not occur.

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6
Q

What is a vector

A

“biting bugs”. provide a means of transmission from host to host

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7
Q

What are three differences between Ecto- and Endo- parasites

A

Ecto: live on the surface of the host, may only be there briefly, and some of them are vectors. Endo: live in the body of host, live in the host for long periods of time, and usually are CARRIED by vectors.

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8
Q

What is a NGD

A

Neglected Tropical Diseases are several parasitic, bacterial, viral diseases that cause substantial illness for more than one billion people globally, but affect only the worlds poorest population.

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9
Q

What are 6 different ways the parasite evades the immune system

A

1.coats itself in the host’s proteins in order to disguise itself
2. Vary its surface antigens: antigenic variation
3. hides inside white blood cell
4. different stages of parasite life have different antigens
5. causes an anti-inflammatory response to suppress immune system
6. cuts antibodies in half

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10
Q

What is the difference between antibiotics and antiparasitics

A

antibiotics attack prokaryotic structures, whereas antiparasitics attack eukaryotic structures

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11
Q

Why are antiparasitic drugs so hard to find and why are they so risky

A

they are risky because they attack eukaryotic structures, which include humans. In order to prevent this, antiparasitic drugs must be made for one type of specific parasite in order for the drug to only hit the parasite and prevent it from hitting humans, which is why we need to know a lot about a parasite before we can learn to treat it.

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12
Q

What are prophylactic drugs

A

preventative pills as to not get the parasite in the first place

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13
Q

face mites: type, primary host

A

ecto, humans

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14
Q

head lice: type, primary host

A

ecto, humans

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15
Q

toxoplasmosis: type, primary host, secondary host

A

endo, cats, prey (birds/rats)

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16
Q

dracunculiasis: type, alt name, primary host, secondary host

A

endo, guinea worm, humans, copepod

17
Q

onchocerciasis: type, alt name, primary host, secondary host, vector

A

endo, river blindless, humans, blackfly, blackfly

18
Q

schistosomiasis: type, alt name, primary host, secondary host

A

endo, bilharzia, humans, snail

19
Q

lymphatic filariasis: type, alt name, primary host, secondary host, vector

A

endo, elephantiasis, humans, mosquito, mosquito

20
Q

malaria: type, primary host, secondary host, vectorq

A

endo, mosquito, humans, mosquito

21
Q

trypanosomiasis: type, alt name, primary host, secondary host, vector

A

endo, sleeping sickness, tse-tse fly, human, tse tse fly

22
Q

what disease can be prevented by clean drinking water

A

guinea worm

23
Q

what disease can be prevented by clea n bathing water

A

schistosomiasis

24
Q

what disease can be prevented bycooking food thoroughly

A

pork tapeworm

25
Q

what are the three targets for a vaccine against malaria

A

1 prevent malaria from leaving the mosquito . 2. prevent malaria from entering the blood stream 3. prevent malaria from getting into red blood cells

26
Q

what are the 5 classes of immunoglobulins

A

IgA, IgM, igD, IgE, and IgG.

27
Q

what class of immunoglobulins are most important for parasitic infections and why?

A

IgE, employed as long-term defence

28
Q

define function of IgG

A

account for 80% of all antibodies, responsible for resistance against viruses, bacteria, and bacterial toxins

29
Q

define function of IgE

A

attaches to individual molecule of mast cells, responsible for fighting parasitic infections

30
Q

define function of IgM

A

first class of antibody secreted. igM concentration declines as igG production accelerates.

31
Q

define function of IgA

A

found primarily in secretions, attack pathogens before they gain access to internal tissues

32
Q

IgA switches to?

A

IgE

33
Q

IgM switches to?

A

IgG

34
Q

What is the link between IgE and allergies?

A

IgE fights off both parasites and allergies and the link is due to mast cells.

35
Q

Explain the process of an allergy in terms of the immune response (4-steps)

A
  1. Allergen gets into the system and attaches to a B-cell 2. IgE antibodies are produced. 3. Antibodies attach themselves to mast cells, which are supposed to release chemicals to fight infection. 4. a second exposure triggers an immune response as the chemicals get released and causes symptoms
36
Q

what are mast cells and why do they exist

A

mast cells are cells that release chemicals in order to destroy pathogens because white blood cells are too small to engulf parasites.

37
Q

behavioural method to break chain of infection

A

avoid being bitten: repellent, avoid rivers

38
Q

what are 3 issues that are associated with vector control

A

high control, vectors are missed, and safety equipment must be available

39
Q

why is resistance a problem

A

short life cycle contributes to fast evolution and adaption