Parasites Flashcards
what is the mode of transportation for Entamoeba histolytica?
fecal oral/ oral anal
Clinical presentation of Entamoeba histolytica
• Amebic colitis / Amebic dysentery (invasive, so bloody diarrhea with blood + PMNs)
• Trophozoite (vegetative form)→ disintegrates to form a cyst (infectious form) → stomach acid breaks it apart →parasite enters the colon → multiplies, vegetates and invades
• Amebic liver abscess
Flask-shaped ulcers →
Diagnosis of Entamoeba
serology and/or trophozoites or cysts (multi-nucleated) in the stool
Treatment of Entamoeba
- Noninvasive disease: paromomycin
* Invasive disease: metronidazole
Mode of transportation: Giardia lamblia
Contaminated water
• Fecal-oral transmission
• Sylvatic distribution in streams, lake
• * Beaver fever → exists as a commensal in beavers
Clinical presentation: Giardia lamblia
- Foul-smelling stools, cramping, explosive watery diarrhea
- Malabsorption syndrome: steatorrhea → fat in the stool
- Malodorous, mushy, greasy stool
Diagnosis: Giardia lamblia
trophozoites or cysts in stool; pear-shaped; 2 nuclei the same
Treatment: Giardia lamblia
metronidazole
Mode of transmission: Balantidium coli
fecal oral; Reservoir is pigs → boar hunter, slaughterer, farmer
Clinical presentation: Balantidium coli
bloody diarrhea;
Treatment: Balantidium coli
Tetracylcine
Mode of transmission: Isospora belli
contaminated water/food. oral/anal
AIDS patients susceptible
Clinical presentation: Isosopra belli
Mimics giardiasis with malabsorption
loose-foul smelling stools
chronic weight-loss, anorexia, malaise and fatigue can be seen
Diagnosis: Isospora belli
- Stains acid-fast
* Iodine-stained stool smears used in diagnosis
Treatment: Isospora belli
• TMP-SMX
Mode of transmission: cryptosporidium
- Water-borne
- Oocyst is stable and able to resist chlorination → will be found in bodies of water, including residential or community pools
- AIDS patients are susceptible
Clinical Presentation: cryptosporidium
- “Crypto”: frequent, explosive, watery diarrhea → dehydration and vomiting
- In AIDS patients, > 50 stools/day that can last for month to years
Diagnosis: cryptosporidium
cysts on stains acid-fast
Treatment: crptosporidium
prevention; Replace fluid and electrolytes
Mode of transmission: cyclospora cayetanensis
- Acquired from contaminated water or food
- Raspberries in Guatemala
- Basil in Mexico
Clinical presentation: cyclospora cayetanensis
- Similar to “Crypto”
* Explosive, watery diarrhea
Diagnosis: cyclospora cayentanensis
Stains acid-fast
Fluoresces blue under UV light
Treatment: cyclospora cayen
• TMP-SMX
Mode of transmission: Enterobius vermicularis (pinworm)
- Endemic in the U.S., especially in children
- Fecal-oral transmission
- Acquired by ingestion of sticky eggs and autoinfection
Clinical Presentation: Enterobius vermicularis
- Intense perianal nocturnal itching
* Females lay their eggs around the anus, which are removed and transmitted as the children scratch their “botitos”
Diagnosis: Enterobius vermicularis
Cellophane tape used for diagnosis
Treatment: Enterobius vermicularis
- Pyrantel pamoate (OTC)
* Mebendazole or albendazole (Treat whole family)
Mode of transmission: Ascaris lumbricoides (roundworm)
- Fecal-oral transmission
* Acquired from food or water as ingested eggs