Parasite Evolution 1 Flashcards

1
Q

Q: How can knowledge of evolutionary processes be used to predict the structure (FST) of parasite subpopulations?

A

A: By understanding factors like gene flow, mutation, and genetic drift, we can predict if a parasite population is likely to have high or low genetic differentiation (high FST means more differentiation).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Q: What are potential outcomes of parasite-host coevolution?

A

A: Outcomes can include genetic adaptations in both parasite and host, selective sweeps, frequency-dependent selection, and evolutionary changes in traits like infectivity and resistance.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Q: What is evolved avirulence, and when might it be advantageous or not?

A

A: Evolved avirulence occurs when a parasite becomes less harmful over time, which can increase its transmission potential. It is advantageous if it promotes longer host survival, but may not be if high virulence increases transmission opportunities (e.g., by intermediate hosts needing to be eaten).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Q: Define microevolution.

A

A: Microevolution refers to evolutionary changes below the species level, observable over a few generations.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Q: Define macroevolution.

A

A: Macroevolution is the study of large-scale evolutionary patterns at or above the species level, occurring over thousands to millions of years.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Q: What are the five major evolutionary processes driving microevolution?

A

A: Mutation, genetic drift, gene flow, natural selection, and nonrandom mating.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Q: What is a mutation, and how does it affect genetic diversity?

A

A: A mutation is a change in DNA that can introduce new genetic variants, increasing diversity within a population.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Q: Are mutations always beneficial?

A

A: No, mutations can be neutral, beneficial, or harmful, depending on the ecological context.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Q: What is genetic drift?

A

A: Genetic drift is the change in allele frequencies in a population due to random chance, often reducing genetic diversity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Q: What is a population bottleneck?

A

A: A population bottleneck occurs when a large portion of a population is wiped out, leaving only a few individuals and drastically reducing genetic diversity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Q: What is the founder effect?

A

A: The founder effect is the reduced genetic diversity that occurs when a new population is established by a small number of individuals from a larger population.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Q: What is gene flow?

A

A: Gene flow is the transfer of alleles between populations, often due to migration, which generally makes populations more genetically similar.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Q: What is natural selection?

A

A: Natural selection is the differential survival and reproduction of individuals due to heritable traits that increase their fitness.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Q: How does natural selection affect genetic variation?

A

A: Natural selection tends to reduce genetic variation by removing disadvantageous alleles.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Q: Describe three types of selection on quantitative traits.

A

A: Stabilizing selection preserves the average phenotype, directional selection favors extreme phenotypes in one direction, and disruptive selection favors extreme phenotypes in both directions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Q: What is frequency-dependent selection?

A

A: Frequency-dependent selection occurs when the advantage of a phenotype depends on its frequency in the population, such as rare phenotypes being more favorable.

17
Q

Q: What is nonrandom mating, and how does it affect genetic variation?

A

A: Nonrandom mating occurs when individuals select mates with specific phenotypes, leading to isolated subpopulations and increased genetic variation.

18
Q

Q: What is the FST index?

A

A: FST measures genetic differentiation between subpopulations, with values ranging from 0 (high similarity) to 1 (high differentiation).

19
Q

Q: Why is a high FST index significant?

A

A: High FST suggests greater differentiation and increased potential for further divergence, possibly leading to speciation.

20
Q

Q: What is effective population size (Ne)?

A

A: Ne is the number of individuals in a population that actively contribute to the next generation, often smaller than the census size and indicative of genetic drift impact.

21
Q

Q: How might a parasite with a complex life cycle have a high FST?

A

A: Due to bottlenecks and varied selection pressures across hosts, which increase genetic differentiation among parasite populations.

22
Q

Q: How might a parasite with highly mobile hosts have a low FST?

A

A: High gene flow between subpopulations limits genetic differentiation, keeping FST low.

23
Q

Q: What is parasite-host coevolution?

A

A: It is the ongoing, reciprocal evolutionary change between a parasite and its host, influencing traits like infectivity and resistance.

24
Q

Q: Give an example of coevolution from nature.

A

A: The interaction between Daphnia magna and its bacterial parasite Pasteuria ramosa, where both have adaptations in response to each other.

25
Q

Q: What is a selective sweep?

A

A: A selective sweep is when a new, advantageous trait replaces an old one within a population.

26
Q

Q: How does frequency-dependent selection play a role in coevolution?

A

A: In parasite-host interactions, rare host genotypes may have a survival advantage due to reduced parasite adaptation.

27
Q

Q: Describe the interaction between Microphallus trematodes and Potamopyrgus snails.

A

A: Parasites target common snail clones, favoring rare clones, which can drive the evolution of parasite targeting strategies.

28
Q

Q: What is virulence, and how might it evolve?

A

A: Virulence is the degree of harm a parasite causes its host; it may evolve to be lower over time to increase the parasite’s transmission opportunities.

29
Q

Q: Explain evolved avirulence with an example.

A

A: The myxoma virus in Australian rabbits became less virulent over time, allowing infected rabbits to survive longer and spread the virus more effectively.

30
Q

Q: Why might high virulence be maintained in some parasites?

A

A: If high virulence increases transmission (e.g., through host sacrifice or bodily fluids), it may be favored by natural selection.