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Pathology > Paraneoplastic Syndromes > Flashcards

Paraneoplastic Syndromes Flashcards

1
Q

Acanthosis nigricans

A

Gastric adenocarcinoma
Other visceral malignancies
(MC associated with obesity and insulin resistance)

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2
Q

Sign of Lester-Trelat

A

GI adenocarcinomas

Other visceral malignancies

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3
Q

Hypercalcemia

A

PTHrP
Squamous cell carcinomas of lung/head/neck
Renal/bladder/breast/ovarian cancer
Increased vitamin D3 (calcitriol): lymphoma

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4
Q

Cushing syndrome

A

Small cell lung cancer (increased ACTH)

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5
Q

Hyponatremia (SIADH)

A

Small cell lung cancer

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6
Q

Polycythemia

A 
Renal cell carcinoma
Hepatocellular carcinoma
Hemangioblastoma 
Pheochromocytoma
Leiomyoma
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7
Q

Pure red cell aplasia

A

Thymoma

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8
Q

Good syndrome (hypogammaglobulinemia)

A

Thymoma

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9
Q

Trousseau syndrome (migratory superficial thrombophlebitis)

A

Adenocarcinomas, esp. pancreatic

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10
Q

Nonbacterial thrombotic (marantic) endocarditis

A

Sterile platelet thrombi

Adenocarcinomas, esp. pancreatic

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11
Q

Anti-NMDA receptor encephalitis

A

Ovarian teratoma

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12
Q

Opsoclonus-myoclonus ataxia syndrome

A

Neuroblastoma (children)

Small cell lung cancer (adults)

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13
Q

Paraneoplastic cerebellar degeneration

A

Small cell lung cancer (anti-Hu)
Gynecological and breast cancers (anti-Yo)
Hodgkin lymphoma (anti-Tr)

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14
Q

Paraneoplastic encephalomyelitis

A

Small cell lung cancer (anti-Hu)

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15
Q

Lambert-Easton myasthenia syndrome

A

Small cell lung cancer

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16
Q

Myasthenia gravis

A

Thymoma

17
Q

Barrett’s

A

Esophageal adenocarcinoma

18
Q

HIV

A

CNS lymphoma

19
Q

Psoriasis

A

HCC

20
Q

UC

A

Colon adenocarcinoma

21
Q

Poly-/dermatomyositis

A

All cancers, esp. GU

Pathology (5 decks)

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