Paramedic Drug Week 8 Flashcards
Succinylcholine (Anectine)
CLASS
Depolarizing neuromuscular blocker, paralyzing agent
Succinylcholine (Anectine)
MECHANISM OF ACTION
Bind to the receptors of acetylcholine.
Succinylcholine (Anectine)
INDICATIONS
To facilitate intubation, to terminate laryngospasm, to promote muscle relaxation, and to facilitate electroconvulsive shock therapy.
Succinylcholine (Anectine)
CONTRAINDICATIONS
Acute narrow angle glaucoma, penetrating eye injuries, inability to control airway or support ventilations with oxygen and positive pressure.
Succinylcholine (Anectine)
SIDE EFFECTS
Apnea, malignant hyperthermia, arrhythmias, bradycardia, hypertension, hypotension, cardiac arrest, hyperkalemia, increased intraocular pressure, fasciculations, exacerbation of hyperkalemia in trauma patients
Succinylcholine (Anectine)
DRUG INTERACTIONS
Effects potentiated by oxytocin, beta-blockers, and organophosphates.
Diazepam may reduce duration of action.
Succinylcholine (Anectine)
ADULT DOSE
1 -2 mg/kg rapid IV; repeat once if needed
Succinylcholine (Anectine)
PEDIATRIC DOSE
1 – 1.5 mg/kg dose rapid IV/IO; repeat once if needed
Succinylcholine (Anectine)
ONSET
1 MINUTE
Succinylcholine (Anectine)
PEAK EFFECT
1-3 MINUTES
Succinylcholine (Anectine)
DURATION
5 MINUTES
Succinylcholine (Anectine)
SPECIAL CONSIDERATIONS
If the patient is conscious, explain the side effects prior to administration. Consider premedication with atropine, particularly in pediatric patients. Premedication with lidocaine may blunt any increase in intracranial pressure during intubation. Diazepam or midazolam should be used in any conscious patient undergoing neuromuscular blockade.
Pancuronium (Pavulon)
CLASS
Nondepolarizing neuromuscular blocker/paralytic
Pancuronium (Pavulon)
MECHANISM OF ACTION
Binds to the receptor for acetylcholine at the neuromuscular junction.
Pancuronium (Pavulon)
INDICATIONS
Induction or maintenance of paralysis after intubation to assist ventilations.