Paramedic Drug Week 16 Flashcards

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1
Q

Labetalol (Normodyne, Trandate)

Class

A

Selective alpha (a1) and non-selective beta(b1-b2)-adrenergic blocker

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2
Q

Labetalol (Normodyne, Trandate)

Mechanism of Actions

A

Reduces blood pressure without reflex tachycardia; total peripheral resistance is reduced without significant alteration in cardiac output

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3
Q

Labetalol (Normodyne, Trandate)

Indications

A

Moderate to severe hypertension

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4
Q

Labetalol (Normodyne, Trandate)

Contraindications

A

bradycardia, bronchial asthma, cardiogenic shock, CHF,

second- or third-degree AV block

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5
Q

Labetalol (Normodyne, Trandate)

Adverse Reactions

A

Headache, dizziness, dyspnea, hypotension, ventricular arrhythmias

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6
Q

Labetalol (Normodyne, Trandate)

Drug Interactions

A

Trandate may block bronchodilator effects of beta-adrenergic agonists. NTG may augment hypotensive effects of Labetalol.

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7
Q

Labetalol (Normodyne, Trandate)

Adult IVP Dosage

A

5-20 mg Slow IVP over 2 min, can give additional dosages of 10-
40 mg at 10 minute intervals.

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8
Q

Labetalol (Normodyne, Trandate)

Adult Infusion Dosage

A

Infusion: 2 mg/min titrated to acceptable

supine blood pressure

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9
Q

Labetalol (Normodyne, Trandate)

Pediatric

A

Safety has not been established

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10
Q

Labetalol (Normodyne, Trandate)

Onset

A

Less than 5 Minutes

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11
Q

Labetalol (Normodyne, Trandate)

Peak Effect

A

Variable

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12
Q

Labetalol (Normodyne, Trandate)

Duration

A

3-6 hours

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13
Q

Labetalol (Normodyne, Trandate)

Special Considerations

A

Continuous monitoring of BP, pulse rate, and ECG. Observe for signs of CHF, bradycardia, and bronchospasm.

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14
Q

Labetalol (Normodyne, Trandate)
Special Considerations
Body Position

A

Should only be administered when the patient is supine.

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15
Q

Furosemide (Lasix)

Class

A

Loop diuretic

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16
Q

Furosemide (Lasix)

Mechanism of Action

A

Inhibits electrolyte reabsorption and promotes excretion of sodium, potassium, and chloride.

17
Q

Furosemide (Lasix)

Indications

A

CHF, pulmonary edema, and hypertensive crisis.

18
Q

Furosemide (Lasix)

Contraindications

A

Hypovolemia, anuria, hypotension (relative

contraindication), hypersensitivity, and hepatic coma.

19
Q

Furosemide (Lasix)

Adverse Reactions

A

May exacerbate hypovolemia, hypokalemia, ECG changes, dry mouth, hypochloremia, hyponatremia, and hyperglycemia (due to hemoconcentration).

20
Q

Furosemide (Lasix)

Drug Interactions

A

Lithium toxicity may be potentiated by sodium depletion. Digitalis toxicity may be potentiated by potassium depletion.

21
Q

Furosemide (Lasix)

Adult Dosage

A

0.5 – 1 mg/kg injected IV over 1 – 2 minutes. If no response, double the dose to 2 mg/kg over 1 – 2 minutes.

22
Q

Furosemide (Lasix)

Pediatric Dosage

A

1 mg/kg/dose IV or IO

23
Q

Furosemide (Lasix)

Onset

A

5 Minutes

24
Q

Furosemide (Lasix)

Peak Effect

A

20 - 60 Minutes

25
Q

Furosemide (Lasix)

Duration

A

4 - 6 Hours

26
Q

Furosemide (Lasix)

Special Considerations

A

Ototoxicity and deafness can occur with rapid administration.

27
Q

Nifedipine (Procardia)

Class

A

Calcium channel blocker

28
Q

Nifedipine (Procardia)

Mechanism of Action

A

Inhibits movement of calcium ions across cell membranes; arterial and venous vasodilator; reduces preload and afterload; prevents coronary artery spasm and decreases total peripheral resistance; reduces myocardial oxygen demand; does not prolong AV nodal conduction.

29
Q

Nifedipine (Procardia)

Indications

A

Hypertensive crisis, angina pectoris, pulmonary edema

30
Q

Nifedipine (Procardia)

Contraindications

A

Compensatory hypertension, hypotension, and

hypersensitivity

31
Q

Nifedipine (Procardia)

Adverse Reactions

A

Hypotension, CHF, headache, dizziness, lightheadedness, nausea, vomiting, muscle cramps, peripheral edema, and myocardial infarction.

32
Q

Nifedipine (Procardia)

Drug Interactions

A

Beta-blockers and theophylline may potentiate the effects. Antihypertensives may potentiate hypotensive effects.

33
Q

Nifedipine (Procardia)

Adult Dosage

A

10 mg SL, may repeat in 30 minutes

34
Q

Nifedipine (Procardia)

Pediatric Dosage

A

0.25 - 0.4 mg/kg

35
Q

Nifedipine (Procardia)

Onset

A

15-30 minutes

36
Q

Nifedipine (Procardia)

Peak Effect

A

1-3 hours

37
Q

Nifedipine (Procardia)

Duration

A

6-8 hours

38
Q

Nifedipine (Procardia)

Special Consideration

A

Use with caution in the geriatric population, may cause hypotension or angina.