paracetamol synthesis Flashcards
1
Q
in 1963
A
paracetamol was added to the British pharmacopoeia and became a popular otc analgesic
2
Q
Paracetamol is
A
Acetaminophen which is a derivative of 4-aminophenol , a nephrotoxin that causes severe centrilobular hepatic necrosis
3
Q
Paracetamol is made of
A
70 parts water , 7 parts alcohol , 13 parts acetone , 40 parts glycerol , 9 parts of propylene glycol , 50 parts chloroform or 10 parts methyl alcohol.
4
Q
paracetamol is soluble in
A
alkali hydroxides
5
Q
paracetamol is insoluble in
A
benzene and ether
6
Q
balanced equation for paracetamol synthesis
A
C6H7NO3 + C4H203 > C8H9NO2 + C2H4O2
