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Derm - 1 > papulosq ds > Flashcards

papulosq ds Flashcards

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Dermatology Board Prep flashcards
1
Q

Genes & Chromosomes associated with Psoriasis

A

HWA CW6 - early onset psoriasis
HLA B27 - Psoriatic Spondylitis
PSORS1 gene - Chromosome 6 - 50% risk

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2
Q

Psoriasis worsening drugs

A

Antimalarials
Lithium
Beta blockers
NSAIDs
Systemic steroids

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3
Q

Psoriasis worsening infections

A

Group A beta hemolytic streptococci - guttate psoriasis
HIV

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4
Q

Epidermal transit time (normal vs psoriasis)

A

28days ➡️ 3-5days

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5
Q

Psoriasis types

A

Plaque psoriasis - mc
Guttate - child, pharyngitis, macrolides
Pustular - sheets/lakes of pus

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6
Q

Acute form of generalised psoriasis

A

Von Zumbusch type

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7
Q

Xray of Psoriatic arthritis

A

Pencil in cup appearance

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8
Q

Psoriatic arthritis classically involves __ joint

A

DIP

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9
Q

Mechanism of phototherapy in psoriasis treatment

A

Increases anti-inflammatory cytokines

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10
Q

DOC for pustular psoriasis

A

Acitretin (oral retinoid)

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11
Q

Role of systemic steroids in psoriasis

A

Sys steroids are c/i in psoriasis, except Pustular psoriasis of Pregnancy (impetigo herpetiformis)
2nd DOC - Cyclosporine

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12
Q

Triggers of Lichen Planus

A

Dental amalgam (m/imp)
Hep C, Hep B
Anti-malarials

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13
Q

6 P’s

A

PRURITIC
Purple
Polygonal
Plain top
Papules & Plaques

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14
Q

Distribution of LP

A

Flexor surfaces

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15
Q

Changes in LP of nail; mc and m/characteristic

A

Thinning of nail plate - mc
Pterygium of nail - m/char
Absence of nail plate (anonychia)

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16
Q

LP - hair

A

Scarring alopecia, showing perifollicular blue grey hue

17
Q

Histopathology of LP

A

Hyperkeratosis of SC
Wedge shaped Hypergranulosis of SG
Acanthosis of SS
Necrotic keratinocytes

18
Q

Pytriasis rosea course

A

Mother/herald patch ➡ Oval/Secondary patches ➡ Pigmentary changes ➡ Resolves in 4-6wks

19
Q

Pytriasis rosea distribution

A

Christmas tree pattern:
Long axis: Down and out from spine, parallel to ribs along lines of Langer

20
Q

Treatment of Pytriasis rosea

A

Counsel pt (4-6wks)
Itchy lesions - steroids, anti-histamine
Recalcitrant - Narrow band UV-B phototherapy (311+/-2nm)

21
Q

Pytriasis rubra pilaris

A

Follicular papules around hair follicles ➡ Progresses to orange red erythema in cephalocaudal direction

Erythroderma (>90% bsa involved)

Spl ftr: Erythroderma + Islands of sparing

22
Q

Treatment of choice for Pytriasis rubra pilaris

A

Acitretin (Oral retinoids)

Derm - 1 (2 decks)

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