Papers

Question 1

What is the paper for gametogenesis?

Answer 1

Maclennan et al (2015) - aneuploidy/T21 ^ maternal age

Question 2

What is the paper for implantation?

Answer 2

Norwitz et al (2007) - defective implantation (excessive vs inadequate)

Question 3

What is is the paper for CHDs/heart?

Answer 3

Millis et al (2010) - CHDs + maternal obesity (Millies cookies)

Question 4

What are the papers for prenatal diagnosis?

Answer 4

Norton et al (2015) - fetal cell free DNA T21 screening vs standard screening

Oever et al (2015) - cffDNA HD (CAG repeat –> PCR)

Frolov et al (2010) - gastroschisis vs omphalocele RFs

Question 5

What is the paper for NTDs / fetal surgery

Answer 5

Maselli et al (2016) - advances in fetal (imaging) + surgery

Adzick (2011) –> NTD repair prenatal vs post-natal

Question 6

What are the papers for placentation?

Answer 6

Silver et al (2015)

Question 7

What are the papers for twinning?

Answer 7

Hall et al (2013) - twins

Poulsen et al (2007) - epigenetics

Question 8

What are the papers for face + palate?

Answer 8

Moriaka et al (2006) - primary repair of CLP adults (vs infants)

Johansson et al (2003) - parents experiences (20 mothers/12 fathers)

Question 9

What are the papers for teratology?

Answer 9

Gupta et al (2016) - FAS (indian drinking)

Kim et al (2011) - thalidomide

Question 10

Describe Moriaka et al (2006) review?

Answer 10

129 adults surgical repair (primary) of cleft palate and lip in dveeloping countries (Nepal and cambodia)

Surgeons experiences

compared to children:

• aggressive correction possible (maxillary growth not a consideration as w/ children)
• correction of anterior nasal deformity more difficult in adults - less elasticity
• More complications in adults (e.g. oronasal fistula)