Papers Flashcards
Elective neck dissection
VS US every 3 months?
Anil de Cruz Tata
On of the few RCTs in the specialty
Depth of invasion is important - less than DOI 3mm can be observed.
cetuximab vs cysplatin for crt for HPV+ OPC? Study name
Rtog 1016 and de escalate - cetuximab is worse comparing to cysplatin for crt
NavDX trial?
NavDX trial at Mskcc - before the surgery. If high, do oropharyngeal tumor resection, monitor based on NAVDX.
When to radiate salivary gland tumors?
Armstrong 1992 paper
Salivary gland indications to RT
High grade tumor radiate and stage III-IV and with nodal mets
Schwannoma treatment paper?
RT paper from Princess Margaret - tumor growth arrest
Surgery, observation is the option.
Neck Mets patterns of scc cancer. Paper
J Shah,
1990 paper of 1119 radical neck dissections.
Oral cavity - 1-3
Oro pharynx and lower - 2-4
Adenoid cystic carcinoma (cylindroma) of the larynx - nodal mets frequency is around ?
Lung mets frequency?
Ferlito (with Shaha) - nodal mts frequency is around 12.1%
Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review 2016
Adenoid cystic carcinoma (cylindroma) of the head and neck - nodal mets frequency is around?
Ziv Gil. - Israel
Incidence of cervical lymph node metastasis and its association with outcomes in patients with adenoid cystic carcinoma. An international collaborative study
Oral cavity - 37%
Major salivary gland - 19%
Frequency of DM in adenoid cystic carcinoma of major salivary glands?
20% overall
67% lung
17% Liver
Prognosis and risk factors for early-stage adenoid cystic carcinoma of the major salivary glands
Mihir K Bhayani 1, Murat Yener, Adel El-Naggar, Adam Garden, Ehab Y Hanna, Randal S Weber, Michael E Kupferman
Osteoradionecrosis - treatment? Paper author?
upfront free fibula flap, better QOL
Resection and immediate microvascular reconstruction in the management of osteoradionecrosis of the mandible
A R Shaha 1, P G Cordeiro, D A Hidalgo, R H Spiro, E W Strong, I Zlotolow, J Huryn, J P Shah - 1997
CRT vs only RT for head and neck cancer?
Two trials
EORTC trial no. 22931 and RTOG trial no. 9501
Elective Neck dissection for parotid malignancy?
2014 Ian Ganly paper
In patients with cN0 disease, observation of the neck is safe in those who are under 60 years of age with clinical T1 or T2 tumors and who have low-grade histology.
END should be carried out in patients with cT3-T4 disease or high-grade histology and should involve levels II to IV at a minimum.
Patients with cN? disease commonly have all neck levels involved and therefore should be managed with comprehensive neck dissection.
Field cancerization concept?
Slaughter 1953, 783 patients
Chicago , university of Illinois
Mslt 1 and 2 trials ?
Melanoma SLNB and neck dissection
ND does not prolong survival. Only Locoregional recurrence free time. And give prognostic information
Orator update ?
No survival difference.
Robot has slight lower Qol - 3 years out
RT complications will kick in later )
