Paper 3 Flashcards

1
Q

Infectious

Q.Atypical lymphocytes are found in -

A

A.Mumps
B.Rubella
C.Dangue
D.EBV
E.HIV

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2
Q

Immunology

Confirmatory diagnosis of anaphylaxis?

A

Serum mast cell tryptase

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3
Q

Infectious

Autoinfection caused by?

A

যাদের বুকের ভিতর আগুন💥💥 জ্বলে তাদের autoinfection হতে পারে।

parasite causes Autoinfection :
CHEST
C-Cryptosporidium
H-H.Nana
E-E.V
S-S.S
T-T.solium

এইগুলো দিয়ে ইনফেকশন হলে Auto বুকে আগুন 💥💥জ্বলবে।

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4
Q

infectious

Return traveller with Abdominal pain and gradual onset bloody diarrhoea with long incubation period highly suggestive of?

A

Amoebiasis

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5
Q

infectious

Overgrowth of which organism most likely to cause Bacterial vaginosis?

A

Gardenella

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6
Q

Infectious

#STI

What are the diseases and organisms causing those?

  1. Painless Ulcer + Painless Lymph Node….?
  2. Painless Ulcer + Painful Lymph Node?
  3. Painful Ulcer + Painful Lymph Node?
  4. Painful Ulcer+ Painless Lymph
    Node?
A
  1. Syphillis
  2. LGV, Granuloma Inguinale(less involve LN)
  3. Chancroid, Genital Herpes
  4. Anal Chancre.
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7
Q

infectious

1.Commensals kf oral cavity?

A

AC তিনটা A, আর candida

-Alpha hemolytic streptococcus
-Actinomyces
-anerobic gm negative(fusobacterium,prevotella)
-Candida

★★★মুখে staphylo নাই

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8
Q

infectious

1.commensal of Nares

A

staphylococcus (সব)

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9
Q

infectious

Commensals of skin?

A

1.Staphylococcus
2.corynebacterium spp
3.prorionibacterium
4.Malassezia

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10
Q

infectious

Commensal of vagina

A

Bcg sle

Bacteroids
Candida,corynebacterium
GBS,gardenella
St,Aureus
Lactobacilus
Enterobacteriacea

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11
Q

Which PG is responsible for fever in preoptic nucleus of hypothalamus?

A

Pg E2

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12
Q

Infectious

1.What are normal human Immunoglobulins (pooled IGl & what are specific?

A

1.Normal:Measles,Hep A

2.Specific:Hep A,Rabies,Tetanus.c.pox

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13
Q

Infectious

1.Live vaccines?

A

Vari MORTal

Varicella zoster
MMR
OPV
ROTA
TYPHOID,TB

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14
Q

Infectious

What are killed vaccine?

A

RICH

Rabies,IPV,influenza,Cholera,Hepa A

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15
Q

Infectious

Viral vector vaccines?

A

1.Covid 19
2.Ebola
3.Dengue

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16
Q

Infectious

Nucleic acid vaccine?

A

1.Covid 19
2.Ebola

17
Q

Infectious

What are 30S ribosome inhibitors?

A

1.Aminoglycosides
2.Tetracycline

18
Q

Infectious

50s inhibitors?

A

1.Chloramphenicol
2.Macrolides(erythtomycin)
3.Lincosamines(clindamycin)
4.Linezolid
5.Fusidic Acid

19
Q

Infectious

Nucleic Acid inhibitors?

A
  1. Nucleotides inhibitions :
    ★Sulphonamides:dihydropteroate inhibitions
    ★Trimethoprim:Dihydrofolate synthase inhibitions

2.RNA inhibitions : Rifampicin
3.DNA inhibition: Fluoroquinolones,Metronidazole

20
Q

Infectious

M/A of quinolones?

A

DNA synthesis inhibitor

21
Q

Infectious

Cell membrane inhibition?

A

Polymixin
Daptomycin

22
Q

Infectious

M/A of anti TB?

A

1.Rifampicin-RNA synthesis inhibitor
2.Isoniazid-Inhibit mycolic acid synthesis
3.Pyrazinamide- inhibit fatty acid synthesis
4.Ethambutol-inhibit arabinogalactan synthesis

23
Q

Infectious

Anti pseudomonal?

A

মনে রাখব ABC + Meropenem

1.Aztreonam
2.Brodactum(piperacillin Tazobactum)
3.Ciprofloxacin,cefepime,ceftazidime
4.Meropenem

24
Q

Infectious

Anti MRSA?

A

1.Clindamycin
2.Linezolid
3.Co trimoxazole
4. Vancomycin
Tigecycline,rifampicin,tetracycline

25
Q

Infectious

Resistence

A

1.By efflux pump:
★Tetracycline
★fluconazole

টেট্রা আর ফ্লুকোনাজল কে লাত্থি দিয়ে বের করব।

২.Impermeable:

★Carbapenem
★Aminoglycosides
কারবাপেনাম আর এমাইনোগ্লাইকোসাইড কে ঢুকতেই দিবে না।
আমিনের কার ঢুকতে দিবে না। আমিন-Amino,কার -Carbapenem

3.Enzymatic degradation:
★Penicillinase:Beta lactam
★NDM1:Enterobactetiacae
★CAT:Chloramphenicol in staphylococcus

4.Modification of target site (বাকী সব গুলা)

★MRSA- to Beta lactum Modification of PBP
★Glycoprotein(vancomycin) resistance in Enterococci-Altered peptidoglycan aminoacid sequence.
★Rifampicin in MTB: RNA polymerase mutation
★ciprofloxacin(quinolones) in Enterobactetiacae : DNA gyrase alteration
★Linezolid in staphylococcus & Enterococci- 23 S rRna methylation
★Macrolides: Bacterial ribosomal Methylation
★Vancomycin- D ala D Ala to D ala D Lac

26
Q

Infectious

Which is the only indication of spectinomycin?

A

Gonococcal urethritis in PG

27
Q

Infectious

Post transplan infection

A

★Solid organ

0-1 month: Bacteria,fungal infection related to underlying condition and surgery

1-6 month: CMV,PCP

> 6 month: বাকী সব

★Post stem cell:

0-4 wks: Bacterial,fungal HSV reactivation

Early <100 days :
CMV
PCP

late>100: বাকী গুলা

28
Q

Infectious

Blood stream infections.

A

1.Predominant Community acquired:

Streptococcus গুলা (entero coccus বাদে)

2.Both:
E.COLI & st. aureus (including MRSA)

  1. Predominantly hospital acquired:
    st epidermidis,pseduomonas,enterobacteriace (except E.coli) Enterococci,Candida
29
Q

Infectious

কোন দুইটা colon ca এর সাথে রিলেটেড

A

S.galolyticus
Clostridium septicum

30
Q

Which organisms are responsible for Necrotizing fascitis in Marine exposure & CLD?

A

1.Aeromonus Hydrophilia
2.vibrio vulnificus

★Necrotizing fascitis type 3 করবে।
★Type 2 - streptococcal toxic shock syndrome এর সাথে Association

31
Q

Commonest regimen for HAART

A

ইফা র এম টেন
Efavirenz or Raltegravir plus Emtricitabine plus Tenofovir

দুইটা NRTI সাথে অন্য গ্রুপের একটা।
Efavirenz avoided in PG

32
Q

Respiratory

Lung compliance : প্রতি ১ cm H20 transpulmonary pr বাড়লে লাং ২০০ ml এক্সপান্ড করে।

increase compliance?

A

1.AGe (OlD age>child)
2.Emphysema(obstructive disease)
3.Sranding

33
Q

Respiratoty

Repeated sino Pulmonary infection + Bronchiectasis

A

Young syn.

34
Q

Respiratory

Features of primary TB due to Hypersensitivity?

A

End diastolic pr is due to primary tb hypersensitivity

1.Erythema nodosum
2.Dactylitis
3.phlyctenular conjunctivitis

35
Q

Non pulmonary complications of pulmonary TB?

A

1.Empyema Necessitans
2.Laryngitis
3.Enteritis,Anorectal disease
4.Amyloidosis
5.poncents arthropathy