paper 1 bio saq Flashcards
research methods & MRI
Maguire 2000s
neuroplasticity (neural pruning & neural network) study & theory
Maguire 2000s
Neuroplasticity is development of neural networks via repetition 2 increase synaptic connections between neurons (neural pathways)
involves neural pruning, (deterioration of synaptic connections of unused neural networks) to form new neural networks
localisation
Maguire 2000s
neurotransmitters study & theory
Rogers & Kesner 2000s
Neurotransmitters - chemical messengers 2 transmit nerve signals between neurons @ synapses, via binding 2 receptors @ post synaptic neuron.
Agonists amplify neurotransmitters, Antagonists reduce
Synpapses r pathways 4 neurons 2 send messages 2 1 another & neurotransmitters carry out these messages via the synpase
Excitatory Neurotransmitters enhance transmission of nerve impulses
Inhibitory Neurotransmitters suppress transmission
hormones study & theory
Meaney 80s
Hormones - chemical messengers of the body
effects are slower acting but for longer periods.
evolutionary explanations for behaviour
Wedekind 90s
genetic similarity
Gottesman & Shields 90s
genes / genetics study & theory
Gottesman & Shields 90s
genes - DNA instructions 4 structure, & function of body, & behaviour.
pheromones study & theory
Wedekind 90s
pheromones - chemical substances externally released & influence behaviour of others
Maguire 2000s Study
AIM (MRI, neuroplasticity, localisation)
- investigate the ability for brain 2 undergo plastic changes from increased navigational requirements
- determine role of hippocampus in spatial memory
STUDY
- Correlational Study
- Quasi-experiment
PARTICIPANTS/IV
- taxi drivers
- control
METHOD
- MRI scan of ppt brains
- analysed size, density, & volume of hippocampus
RESULTS
- larger hippocampus
- hippocampus volume correlated w time as taxi driver
IMPLICATIONS
- environmental pressures 2 learn navigation made the brain plastic to increase neural pathways shown in increased volume & size of hippocampus
- hippocampus stores spatial information
Rogers & Kesner 2000s Study
AIM (neurotransmitters)
- to investigate effect of acetylcholine in formation of spatial memory
METHOD
- rats acclimated 2 maze & objective 2 find food in opposing corner
- then rats were into 2 groups:
- 1) injected w/ scopolamine—a drug (antagonist) blocks reception & function of acetylcholine as it cannot travel from 1 neuron 2 another
- 2) placebo injection
- After injection rats were placed into maze & measured how long it would take 2 find food across 2 days
- formation of spatial memory: averaging then comparing no. errors made on the 1st & 2nd day
RESULTS
- experimental group took longer to learn the maze, & made more errors
IMPLICATIONS
- acetylcholine effects formation of spatial memories
Meaney 80s Study
AIM (hormones, brain
- investigate effect of cortisol on memory
PARTICIPANTS/IV
- Condition 1 rats: experimental group, neglected rats
- Condition 2 rats: control group
METHOD
- After the rats reached maturation: individually placed in a container with milky water & had to escape by finding a platform
- this process repeated multiple times 2 see whether the rats would use their memory to reach the platform more effectively
- The route the rats took across trials was tracked
RESULTS
- neglected rats secreted more cortisol in response 2 stressful maze than the control rats, & elevated levels of cortisol at rest
- Accelerated hippocampal neuron loss & thus spatial memory deficits due 2 higher cortisol, shown by rats taking ineffective paths at older ages
IMPLICATIONS
- higher level cortisol from prolonged stress leads to hippocampal neuron loss which causes reduced spatial memory abilities
Wedekind 90s Study
AIM
- investigate female attraction of males body odour are dependant on MHC genes (expressed through scent)
METHOD
- all participants had MHC genes identified
- males wore shirt (2 days straight)
- females smelt the shirt & ranked the odour
RESULTS
- females preferred smell of men w dissimilar MHC genes
IMPLICATIONS
- pheromones plays a role in initial attraction
-attracted 2 differing genes 4 genetically diverse offspring (survival of fittest)
Gottesman & Shields 90s Study
AIM
- investigate relationship between genes & developing schizophrenia
PARTICIPANTS
- monozygotic twins (100% shared genes)
- dizygotic twins (50% shared genes)
METHOD
- researchers correlated the likelihood of the other twin develop sz if the other twin had sz via hospital records & interviews w/ twin w/o sz
RESULTS
- MZ around 50%
- DZ less than 20%
IMPLICATIONS
- genetic inheritance influences development of SZ