pap smear cytology criteria

Question 1

ASC-US

Answer 1

criteria less for LSIL, intermediate or superficial cells 
2-3 times nuclei
slight N/C ratio
minimal nuclear hyperchromaia
slightly irregular nuclear conture
clumpning 
smuding 

cells contain 50% risk of HPV

Question 2

ASCUS-H

Answer 2

5% of all ASC
Cytological criteria of HSIL, ut show of criteria
30-40% association with underlying C1N2-3
70-80% have oncogenic risk( HPV)
Atypical immature metaplasti cells
single or cluster of <10 cells
nuclear size 1.5-2 times of meaplastic cells
round to oval nuclei
dense ampophilic cytoplasm
high n/c ration with mildly hyper chromatic
if many cells with high N/C ration,irregular nuclei
and hyperchromastic, facvoyur HSIL