Panda fam med: 1 Flashcards
Two Type 2 diabetic treatments allowed in children?
- Insulin
2. Metformin
What beta blocker is best in CHF treatment?
Carveidolol (Comet Trial)
What are max doses of Lasix / ACE-I?
- Lasix = 80 mg
- ACE-I = 40 mg
If CHF patient is symptomatic on max doses of all meds, next step?
Biventricular Pacing
3 Beta Blockers for CHF Patients
Metoprolol (b1 specific)
Bisoprolol (b1 specific)
Carveidolol (nonspecific with alpha antagonist properties)
Omega 3 Fatty Acids
- Mechanism of Protection
- Long Term Benefits (3)
- Use in high risk patients, esp allergic to ____
- Mechanism: increase eicosonoid production = decrease platelets/increase vasodilation
- 3 Longterm Benefits: decrease stroke, non-fatal MI and arrhythmias
- Good for people allergic to fish
Management for Descending Aortic Dissection:
- Rx (2)
- When to Operate?
Rx:
- Beta Blocker IV
- Nitroprusside: always give BB first b/c this will cause reflex SNS activity which will increase LV output and shear stress on aorta
Operate:
- If ascending component
- If major branches are involved
Recommendations for AAA Screening
All males between 65-75 who have ever smoked. One time screening is recommended unless pathology is found.
LDL Goal for Diabetics
<100
Benign Childhood Murmurs (3)
What components of murmur will NEVER include it in benign murmurs of childhood (3).
- Still’s Murmur: S = S, still’s best heard when supine; musical
- Peripheral Pulmonic Stenosis: systolic murmur radiating to b/l axilla
- Venous Hum: 2/2 fluttering open/close of jugular veins; best heard when UPRIGHT (vs. Still’s) and on INSPIRATION (b/c venous)
NON-BENIGN FEATURES
- Diastolic
- Extra sound
- > 2/6 on Levine Scale
Management of Stable Angina (2)
- Beta Blocker
2. ASA
Indications for thrombolytic therapy in AMI? (2)
Both are on EKG
- Ensure STEMI
- ≥1mm elevation in 2x limb leads
- ≥2 mm elevation in 2x precordial leads - Look for New onset LBBB which is c/w complete occlusion
You suspect secondary HTN in a patient. Knowing one of the MCC, what is the best test to order?
AM Aldosterone/Renin Ratio looking for primary hyperaldosteronism. If ratio >20 = Dx!
Note: Renovascular HTN (with RAS is MCC 2/2 HTN)
Plantar Fasciitis (Etiology, Presentation, Treatment)
- Etiology: 2/2 overuse (repetitive micro trauma) = obese/always on feet
- Presentation: heel pain with “First step phenomenon”, gets better throughout day
- Treatment: OTC Heel Inserts / Achilles Tendon Stretching / NSAID –> Steroid Shot –> Surgery
- Tarsal Tunnel (Etiology, Presentation)
- Etiology: compression of post tibial nerve deep to med malleoulus
- Presentation: medial foot / plantar paresthesias with pain on tapping tarsal tunnel
- Fat Pad Atrophy (Etiology, Presentation)
- Etiology: atrophy of fat pad over heel
- Presentation: pain worsens throughout the day
Best anticoagulation for patient undergoing hip repair who has history of previous post-op DVT?
SubQ Lovenox before and after surgery
Recommendations for Patients with HCM (2)
(T/F) HCM Patients have decrease lifespan
Recs:
- No strenuous activity
- Screen all first degree with ECHO
False. Risk of SCD 1-5%
3 CIs to using Beta Blockers in CHF?
- Bradycardia
- Heart Block
- Severe Asthma
Pre-Op Cardiac Risk
- Protocol
- Classify procedures into High / Int / Low Risk
- Protocol: 12 Lead –> Stress Test if + –> Cath if +
- Classification
1. HIGH RISK: anything vascular / emergency
2. INT RISK: head/neck, thoracic/abdominal, prostate
3. LOW RISK: Breast, Cataract, Endoscopic
Marelgia Paresthetica
Compression of LFCN –> sensory loss of ant/lat thigh without motor deficits
Pt with fatigue, adenopathy and pharyngitis is giving ampicillin / PCN. They develop a morbilliform rash. If this patient is then admitted to the ED with respiratory distress, what is the next best step?
Add steroids. Patient has MONO; airway obstruction 2/2 inflammation. Give steroids.
5 Malignancies associated with EBV?
- Nasopharyngeal Carcinoma
- Primary CNS Lymphoma
- Burkitt’s
- Hodgkins
- (HIV) Hairy Leukoplakia
HyperCa of Malignancy
- 3 Etiologies
- Management Protocol
- 3 Etiologies: PTHrP»_space;> Mets with Release of Local Factors»_space;> Ectopic PTH Secretion
- Management:
1. IVF
2. +/- Lasix to avoid IVF overload
3. Calcitonin (Acute management) vs. Bisophosphonate (chronic management)
Treatment of Torsades?
Mg
10 y/o has older sibling who died suddenly in a soccer game. His parents have had recurrent syncopal episodes.
- What do you suspect?
- Next best diagnostic step?
- Management?
- Suspect Long QT Syndrome
- Diagnostic Step: RESTING (≠Stress EKG) for long QT interval
- Management: beta blockers and NO competitive sports
WPW
- EKG Findings (3)
- Treatment
EKG Findings in WPW
- Short PR Interval
- Narrow QRS
- Delta wave
Treatment: Procainamide
You are considering starting a RA / AI patient on TNF-alpha blocker. What 3 diseases do you screen for?
- Hep B
- Hep C
- TB
Lab Test to W/U Suspected HCV (3 Components)
- ELISA for HCV Antibody
+: Proceed to 2nd Immuno Based Assay (#2 below)
-: Not infected or very early infection - Immunobased Assay for HCV Antibody
+: Proceed to test for active / resolved infection (#3 below)
-: Original ELISA was a false+ - HCV RNA PCR
+: Active Disease
-: Resolved disease
OCD:
- First Line Treatment (2)
- Alternative to First Line Rx Treatment
- First Line Treatment
1. SSRI
2. Exposure-Response Therapy - Alternative
1. Clomipramine
NHAP
- Why to think about different bugs?
- Inpatient vs. Outpatient Management
NHAP: increase colonization of oropharynx with GNR
Management
1. Inpatient: Cover MRSA (Vanc/Linezolid) and 2x Anti-Psuedomonal (Resp Fluoroquinolone and Cephalosporin)
- Outpatient: Resp Fluoroquinolone
Standard Management of Osteoporosis (3 components)
- Lifestyle Change (no smoking, exercise)
- Supplements: 800 VitD + 1200 Ca
- Rx: Bisphosphanate (≠Calcitonin b/c this is more acute management) –> Teriparatide
Rx that Decrease Hip Fractures (3)
All Bisphosophnate: Alendronate, risedronate, zolendronate
Rx for Post-menopausal women with Osteoporosis and FMH of Breast Cancer
Raloxifine: agonist in bone / antagonist in breast
Rx for Men with Osteoporosis (2)
- Alendronate
- Teriparatide
Rx for osteoporosis in Patients on Chronic Steroids
- Supplements (VitD + Ca) and Bisphosphonate
Rx that increase risk for osteoporosis (5)
- Steroids
- Heparin
- Phenytoin (or any CYP - increase Vit D metabolism)
- Thyroid replacement
- Cyclosporin
Influenza
- Microbiology Name
- Management
Orthomyxovirus A/B
Management
48 + Hospitalizations = NA-inhibitors
> 48 and NO Hospitalization = no treatment
ASA PPx Men vs. Female
Men: 45-79 where risk of MI > GI Bleed
Women: 55-79 where risk of Ischemic CVA > GI Bleed
Benign NB Rash (4)
- Erythema Toxicum: ERYTHEMA surrounding macules/papules/pustules. +Eosinophils on smear
- Acne Neonatorum: macules/papules/pustules without surrounding erythema on face.
- Staph Pyoderma: vesicular rash with g+cocci in clusters
- Milia: pearly keratin plugs without surrounding erythema
Patient has symptomatic MVP.
- What are the symptoms?
- Treatment?
Symptoms = palpitations Treatment = Beta Blockers
Subclinical Hypothyroidism
- Clinical Features
- Labs
- Risks (vs. Subclinical Hyperthyroidism)
- Clinical Features: ASYMPTOMATIC (thus “Subclinical”)
- Labs: HIGH TSH (hypothyroid) but NORMAL FT4 (thus Asx)
- Risk: increase LDL / cholesterol
Don’t confuse with subclinical hyperthyroidism = associated with increase sCHF / arrhythmia / decrease bone density
Lithium ADE
What other common Rx causes increase Li levels?
LMNOPP Lithium... Movement Disorder (Tremors) Neph DI hypOthyroidism Pregnancy (Ebstein) High PTH = High Ca
NSAIDs; recall Li is cleared in the kidneys, so anything that simulates AKI or increase resorption (dehydration) will cause increase Li levels.
CI to Breast Feeding (7)
4 Common Misconceptions of CI to Breast Feeding
CI:
- Active HIV
- Active HSV over breast
- Active TB (≠TB Rx)
- Radioactive Iodine
- PO Antifunglas/Antimalarials/Antiparasitics
- Lithium
- Chemotherapeutics
Not CI:
- HepB/C
- CMV
- Warfarin
- Active Mastitis
3 MC Fish Toxicities
- Scombroid: eating poorly stored fish where bacterial infection converts histidine –> histamine = anaphylaxis
- Ciguatera: eating reef fish; manage symptoms
- Shellfish: eating shellfish; manage symptoms
POTS vs. Orthostatic Hypotension
- Criteria
- Underlying pathophysiology for both
POTS
- +30BPM or HR >120 within 10 minutes
Orthostatic Hypotension
- Drop in SBP by 20 or DBP by 10 with increase in HR by 20
Paph
- Loss of baroreceptor responsiveness
- Loss of myocardial contractility
JNC 7 Guidlines for Post-CVA HTN Rx
ACE-I + HCTZ
6 Features of Solitary Thyroid Nodule s/o Malignancy
- H/o Neck Radiation (Papillary)
- > 4.0 cm
- Fixed / Firm
- Signs of Spread (Adenopathy, Dysphagia, Hoarseness)
- Male Gender
- Non-functioning
Approach to Incidentaloma In Thyroid
If:
- <1.0 cm
- Asymptomatic
- Normal TFTs
F/u with Serial USG q6-12 months
(T/F) In growth issues in hypothyroidism, bone age = chronologic age.
False, bone age < chronologic age.
4 Indications for PT-ectomy in HyperPTH
SCAB
- Stones
- Serum Ca >1.0 mg/dL above normal
- Age <50
- Decrease Bone density
Presbycusis
- What type of hearing loss?
- What frequency is affected?
- Consonants vs. Vowels
Sensorineural High frequency (=consonants)
Known Cirrhotic p/w new onset fevers and diffuse abdominal pain.
- Next Best Step
- What will confirm the diagnosis?
- MC Bugs (3)?
- Best treatment
Diagnostic Paracentesis for SBP
Findings on Paracentesis confirming diagnosis:
- PMN >250
- +Fluid Culture
- MC BUg = EColi > Kelb > Strep Pneumo
- Best Treatment = Cefotaxime
At prenatal visit mother is found to be HBsAg+. What actions should be taken to decrease transmission to baby?
At the TIME OF BIRTH, baby should receive:
- HBIg
- HBV Vaccine (normally occurs anyway)
What 4 bugs survive in chlorinated water?
Entamoeba Histolytica
Giardia
Cryptosporidium
HAV
4 Groups of Patients needing screening for HCV?
- IVDU (needles)
- Accidental needle stick
- Transfusions <1987
- Persistent Elevations in LFT***
IBS
- Diagnostic Criteria (3)
- Supplement that helps
- Most consistent finding
Rome Criteria
- Abdominal Pain / Distention (abd pain = MC finding)
- Change in consistency / frequency of stool
- Relief with defecation
Supplement that Helps: Daily Peppermint Oil
In ___(3 diseases)__ correct anemia to ______(value)____.
CHD, CKD and EPO Replacement Patients = 3 Disease
Anemia Correction: 10-12
*Patients who were corrected all the way did worse from CV-related events