pancreatitis Flashcards
1
Q
causes of pancreatitis
x2
A
gallstones
alcohol
40% each approx
2
Q
Gallstones pathway
A
1 bile reflux - damaged mucosa of pancreatic duct
2 duodenal reflex - activation of trypsin
3 increased intraductal pressure - accumulation of pancreatic enzymes
3
Q
Alcohol pathway
A
1 oddi sphincter spasms
2 acinar cell sensitivity to increased CCK which activates protease
3 decreased bicarbonate secretion leads to hyperviscosity
4
Q
Clinical features - symptoms
A
jaundice renal failure shock n + v ascites epigastric pain radiating to the back bruising - grey turner’s = flank - cullen’s = umbilicus
5
Q
clinical features- enzymes
A
amylase x3
lipase is more specific for damage
6
Q
complications x3
A
pancreatic abscess
pseudocyst
peri pancreatic collection
7
Q
management
A
analysis and ng if needed
ERCP for gallstones
if kidney failure due to systemic then dialysis
