Pancreatitis Flashcards
What hormones does the pancreas release
insulin and glucagon
SS of acute attack
sever abd. pain that radiates from the epigastric region to the back.
Fever
N/V
Tachycardia
What are some causes of pancreatitis
MC is ETOH and gallstones
as Drugs= corticosteroids, furosemide.
What genetic dx is linked to pancreatitis
cystic fibrosis
How do you DX and monitor Pancr..
amylase and lipase levels
Chronic Pancreatitis
Similar to acute c wgt loss (malabsorption)
DM- occurs with distruction of insulin-producing cells of the pancreas
Lab Values
WBC-12-20000
HCT increase as high as 50-55% (inflammation)
Hyperglycemia
Serum Ca decreases
Serum bilirubin increase (15-25%) due to pancreatic edema compressing the common bile duct.
Amylase
> 3x the ULN supports dx
increase within 3-6hrs, rapidly within 8hrs, peaks in 20-30hrs.
Returns to normal within 3-5 days
Digests carbs
Lipase
More specific and sensitive then amylase remains elevated for 8-14 days
>3x the ULN is dx.
Increases within 3-6hrs peaks at 24hrs
Less likely to be affected by chronic pancreatis
Digest fats
Other Lab Values
CBC__
Metabolic panel___
C-reactive Protein
CBC=Leukocytosis
Metabolic panel-may show abd. vaules in Ca, BUN, and Glucose
C-Reactive Protein- >150mg/dl within first 72hrs=acute necrotizing pancreatitis. (wait 48hrs before ordering)
A lipase:Amylase ratio >3 suggests?
Alcoholic cause
Admission Criteria
GA-LAW Glucose >200 Age>55 LDH>350 AST>250 WBC>16000
48 hr criteria
C-HOBBS
Ca 10%
Oxygen5
Base Deficit>4 (HCO36L
Score of 0-2
3-5
>5
minimal mortality
10-20% mortality
50% mortality