Pancreatic Disorders

Question 1

Secretin

Answer 1

released from the duodenal mucosa in response to the presence of acid in the duodenum.
stimulates the release of bicarbonate and water.

Question 2

Cholecystokinin (CCK)

Answer 2

released from SI endocrine cells in response to the entry of fats and proteins into the proximal intestine.
acts directly and through vagal afferents to stimulate pancreatic acinar cells to release digestive proenzymes.

Question 3

Pancreatitits Lab Tests

Answer 3

Serum amylase:

Serum lipase: (#1 test for pancreatitis)
sensitivity 82-100%, more specific than amylase

CRP: to monitor disease, not diagnose

Question 4

Virchow’s node

Answer 4

L supraclavicular node, seen in pancreatic cancer

Question 5

Tumors of the head present w/

Answer 5

weight loss, steatorrhea & jaundice

Question 6

Tumors of the body or tail present w/

Answer 6

pain & weight loss

Question 7

Serum tumor maker

Answer 7

CA 19-9 closely related to tumor size, can be elevated in pts w/ benign pancreaticobiliary disorders, serial monitoring can assess the response to treatment