PANCE Flashcards
philadelphia chromosome is pathognomonic of what type of leukemia
CML
Auer rods and Pancytopenia with circulating blast
AML
what type of lymphoma will most likely find epstein bar virus?
hodkins lymphoma
Reed-Sternberg cells =
= Hodgkins lymphoma
X-ray of the skull showing punched out lesions =
multiple myeloma
Thiazide diuretics is contraindicated in which patients?
Gout
what drugs can cause macular degeneration?
chloroquine or phenothazin
patient with strep pharyngitis allergic to penicillin, which abx?
Azithromycin
what is the name of a mass that develops in young adult following URI?
brachial cleft cyst -locateds away from the midline and anterior to the SCM
what is the treatment for oral trush?
nystatin or clotrimazole troches
what causes chronic otitits media?
P. aeuriginosa, H influenza, S. aureus
which type of conjuntivitis will present with pre-auricular lymphadenopathy?
viral conjunctivitis
what is the treatment for gonorrheae?
IM ceftriaxone or oral ceftixime
medications that causes ototoxicity?
aminoglycosides (gentamycin), loop diuretics, antineoplastic agents (cisplatin)
what is the treatment for aphthous ulcer?
liquid dihenhydramine
antacid
tetracycline
2% viscous xylocaine
what is the center criteria?
fever, tonsilar exudates, tender anterior lymphadenopathy, lack of cough
what is aphthous ulcer asssociated with ?
herper virus 6
what is the treatmement of aphthous ulcer?
liquid dihenhydramine
antacid
tetracycline
2% viscous xylocaine
what is prebyscus?
age related bilateral loss of high frequency hearing
what medication will help to relieve pain in the eye due to foreign object or substance?
proparocaine 0.5% opthalmic solution
sudden painless vision loss
cherry red stop on macula along with pallor to the retina, what is the DX?
Central retinal artery occlusion
what is the treatment for giant cell arhtritis?
high dose prednisone 60mg/day
characterized by blood and thunder fundus
mark hemmorrages
torturous vessel
central vein artery occlusion
what is cholesteatoma?
variety of chronic ottitis media
most common cause prolongerd eusthachian tube dysfunction with resultant chronic negative middle ear pressure that draws inward the upper flacid portion of the tympanic membrane
how do you monitored open angle glaucoma?
tonometry
gonioscopy
monitored dics to cup ration
visual field examination when monitoring
what is sialodenitis?
-acute bacterial mc s aureus
affect parotid or submandibular gland
acute swelling of the gland
increased pain and swelling with meals
tx for sialodenitis?
nafcillin
inclussion conjunctivitis fro chlamydial infection?
azithromycin 1g orally
what is herpes simplex keratitis?
causes acute ocular morbidity, virus colonizes trigeminal ganglion
positive D dimer is seen in
DIC
bite cells and heinz body are seen in this type of anemia
G6PD
should not eat fava beans
G6PD deficiency
t/f both hemophilia A&B are both x linked recessive
true
what is the main treatment acute management for anxiety?
SSRI-benzodiazepine (alprozalon or lorazepam)
what is the main treatment for the maintenace of anxiety?
benzodiazepine are tapered.
paroxetine is beneficial, fluoxetine, venlofaxine, sertraline
what is the treatment for schizoprenia?
serotonin and dopamine antagonist
what is clozapine and what is its side effect?
second line therapy to treat schizophrenia and can cause agranulocytosis
what is the difference between schizophenicform disorder and schizphrenia?
Schizophrenicform disorder last about 1-6 months
what is the treatment for body dysmorphic disorder?
serotonin modulator blocks (fluozetine, clomipraine), SSRI @ higher doses -treat for 10-12 weeks
when does pospartum depression occur and what is the tx?
4 weeks after delivery and tx is SSRI-sertraline and also hormone therapy might help
what should a patient be aware when started on MAOIs?
a tyramine free diet (no wine, beer, almost all cheeses, smoked meats , aged foods) to avoid side effects.
what is a side effect of MAOI when patient consumes foods containing tyramine?
hypertensive crisis
what is the treatment for mood disorder?
SSRI (fluoxetine, paraxetine, sertraline)
what is the treatment for atypical depression?
MAOIs
what is serotonin syndrome?
when MAOI are used with SSRI
what is the treatment for bipolar disorder?
acute mania: lithium, antipsychotics, benzos, antisz
commonly lithium or valproate + antipsych
describe the different personality disorder clusters?
cluster A: mad
cluster B: Bad
Cluster C: Sad
what makes up cluster A?
paranoid, schizoid, schizotypal
what are the types of cluster B personality disorder?
Histrionic, Narcissistic, Borderline, Antisocial
what are the subtypes of cluster C?
avoidant
dependent
obsessive-compulsive
causes measles
paromyxovirus
causes rubella
togavirus??
causes foot hand mouth disease
coxsakie virus A16
causes erythema infectiousum
parvovirus b19
causes roseola infantum
HHV6 or 7
HIV, deep, purple, papular lessions
kaposi’s sarcoma
lession> 6mm
possible malignant melanoma
precursor of squames cell carcinoma
actinic keratosis
rouleaux formation seen
mutliple myeloma
autopsy of rabies shows
negri bodies
autops on alzeimers shows
neurofibrillary tangles
periventricular plaques is associated with
multiple sclerosis
slapped check
erythema infectosum
high fever then rash (starts on trunk spreads to face and extremeties)
Roseola
diagnostic test for malaria
peripheral blood smear with Giensa
coryza, cough, conjunctivities, koplik spots
measles-rubella
what is the drug of choice for cases of MRSA?
bactrum
what is herald patch?
salmon color -papular rash seen in pityriasis roseasea
what is the treatment of choice for urticaria caused by ABX
hydroxizine
what leukemia will present with Aeur rods?
AML
leukemia with CNS involvement
ALL
which leukemia will present with smudge cells
CLL
treatment for hemophilia IX
desmopresin
positive philadelphia chromosome seen in
CML
reed sterberg cells
hodkins lymphoma
howell-jolly bodies seen in
macrocytic anemia
ABX m/c to cause GERD
tetracycline
infectious esophagitis endoscopy with deep ulcers
CMV or HIV
infectious esophagitis with shallow ulcers agent
HSV
best initial test to visualized lession in esophagial neoplasm
biphasic barium esophagram
what is Budd Chiari syndrome?
may cause thrombosis of the portal vein leading to esophagial varices
treatment for h pilory
PPI+clarithromicin( or metronidazole) +amoxicillin or
Bismuth subsalicylate tetracycline + metronidazole+ PPI
what is prophylaxis treatment for h pylori
misoprostol or ppi
DX for ZES
secretin test 2 u/kg
tx for clostridium difficile
metronidazole, vancomycin, fidoxamicin
dx test for malabsorption
72 hrs fecal fat test
diagnostic test to distinguish between malabsorption from mladigestion (e.g pancreatic insufficiency)
D Xylose test
diagnostic test for celiac
IgA antiendothelial (EMA) antitissue transglutaminase ( Anti-TTG)
how is the dx confirmed in celiac
small bowel biopsy
what is the treatment for refractory case of celiac
prednisone
what is the treatment for chrons disease
prednisone for acute attacks with or w/o amino salicylates
tx for perianal disease in chrons
metrinadazole or cipro
best tx for maintanence of Chrons
mesalamine
TX for refractory cases of Crohn’s
infliximab
the tx for UC
total protecolectomy
currant jelly stool, sausage mass
intessuception
anal fissure is most likely location
posterior midlne
courvoiseur sign
jaundice and palpable gall bladder indicating pancreatic neoplasm
test to confirm dx of cholecysitis
HIDA scan
test to identify cause, location, extent of biliary obstruction
ERCP
Anti-HAV
onset of Hepatitis
HAV-IgG
resolved disease
HBs-AG
ongoin infection
Anti-HBs-
immunity due to past infection
anti-HBc
immunizatino or acute
c=core
HbeAG
e=envelope
active and contagious
anti-HBe
lower viral titer
HBsAG=
carrier or chronic infection
possible cause of liver abcess
entomoeba histolytica or coliform
direct hernia
hesselback triangle, no scrotum
indirect hernia
internal inguinal ring and scrotum
treatment for pyloric stenosis
riboflavin
failure to pass mecomiun first 48hrs what is the DD?
hirshsprings
cryptococcus causes & TX
fungal meningitis,amphoterecin B plus flucystosis
test for lyme disease
elisa
tx for lyme disease
IV ceftriaxone
boxer’s fracture to the mouth , treat for what organism?
Eikenella corrodens-organism specific to human mouth