Pamacology Flashcards
System of weight / measures ?
Metric System: (measures) Gram measures weight 1kg = 1,000 g 1g = 1,000 mg 1mg = 1,000 mcg The Apothecary System (It is another method of expressing units of measure. It is an old system and is not used exclusively because it is not standardized. That means that each measure is an approximate amount, not an exact amount. But, some doctors still order medicines using this system, and some labels contain this system as well. Grain measure weight and is written gr. gr 1 = 60mg Gr XV = 1g
What are diffrent forms of drug ?
Oral Solids:
Tablets
Scored tablets (lines, markings to cut into 2 or in 4) – for easy division
Enteric coated (protective from the stomach acid)– coating prevents the tablet from dissolving in the stomach, designed to dissolve or be absorb in the small intestine. (DO NOT CRUSH/CHEW!) (time release tabs you don’t crush either)
Capsules
Drug is enclosed in a hard or soft soluble shell, usually made of gelatin or plastic shell
May also contain drug impregnated beads designed to release drugs at different rates
Troches/lozenges (help sooth or numb throat)
Generally disc shaped
Should be dissolved slowly in the mouth. (Do not chew just suck)
Usually release medication that provides an antiseptic or anesthetic effect on the tissues of the oral cavity/throat
Oral liquids:
Solutions:
Syrups-sweetened
Elixirs – contain alcohol
Tinctures- contain alcohol as primary solvent dissolving meds
Douches (vaginal) -used in cleansing part of the body
Solutions that are given IV must be sterile & free of particles that could serve as embolus. (pushed into IV and must be sterile)
Suspensions
Liquid dosage forms that contain drug particles
Most administered orally or sometimes topically or by injection
Should be shaken immediately before administration
Not given IV because has solid particles (could cause a blood clout)
Emulsions (oil in water for nutrition)
Dispersions of fine droplets of an oil in water or water in oil
Must be shaken thoroughly before administering
Oral, topical, or IV
Topical dosage forms:
• Ointments
A viscous semisolid preparation (80% oil/
20% water) used topically on a variety of body surfaces-skin, eye, vagina, nose
Often medicated & more potent than creams
• Creams
A semi-solid emulsion (50% water & 50% oil)
A topical preparation for application to the skin or mucus membranes i.e. rectum or vagina
May or may not be medicated
• Lotions (thinner, lighter & less greasy or oily)
Thinner than creams often packaged in a pump, absorb quickly feel light on the skin
• Transdermal Patches
Medicated adhesive patch placed on the skin to deliver a time released dose of medication through the skin & into the blood stream
Clean & rotate sites
Look for a non hairy place
Put date & time on patch
Make sure old patch is taken off before putting on a new one
Parenteral:
Given by injections via a route other than the GI tract including:
Subcutaneous (SQ)
Intramuscular (IM)
Intravenous (IV)
Intradermal (ID)
Several different ways are used to package sterile medication intended to use an injection
Ampules –Sterile, sealed glass or plastic containers containing a single dose
Vials Single or multiple-dose glass or plastic containers that are sealed with a rubber stopper
Pre-filled syringes - Syringes containing a single dose
External body orifices:
Suppositories – a dosage inserted in external body orifices usually the rectum, vagina, or urethra
Other body orifices: Eye, Ear, nose
Suppositories hold for 30 min for it to dissolve
Rectally give on left side
Inhaled Medications –
inhaler
nebulizer breathing treatment
What are commonly used abbreviations for route , frequency of medication
Gastrostomy tube (GT)
Nasogastric tube (NGT)
Oral (p.o) – oral medication is one that is given by mouth and swallowed
Sublingual (SL) – A sublingual medication is one that is placed under the tongue.
Buccal – A buccal medication is one that is placed in the mouth next to the cheek. It is in tablet form.
Hand held nebulizer (HHN)
Inhalation – medications administered by inhalation are those that are sprayed or inhaled into the nose, throat, and lungs
Meter dose inhaler (MDI)
Rectal- Rectal medications are those inserted into the rectum and are slowly absorbed into the mucous membrane lining of the rectum
Vaginal – Vaginal medication are those inserted into the vagina
Topical – A topical medication is one applied directly to the skin or mucous membrane for a local effect to the area
Transdermal – a method of applying a drug to unbroken skin. The drug is absorbed continuously and produces a systemic effect (packaged in an adhesive-backed disk)
Parenteral – Any route of administration not involving the gastrointestinal tract, e.g., topical, inhalation or injection (parentaral medication for injection must be in a liquid form and administered by one four methods: intradermal, intramuscular, intravenous or subcutaneous
Intradermal (ID) – a small amount of medication is injected just beneath the epidermis
Intramuscular (IM) – The medication is injected directly into large muscles.
Intravenous (IV) – The medication is injected directly into the vein, entering the bloodstream immediately
Intravenous piggyback (IVPB) – wide shape tubing elevated up high and flow in main line like usually an antibiotic. Piggybacking on a main line of IV fluids. Now have IV pumps and don’t have to elevate it.
Intravenous push (IVP)
Subcutaneous (Sub Q) – the medication is injected into the subcutaneous layer, or fatty tissue, of the skin.
Swish and Swallow (S & S)
OU – both eyes
OD – Right eye
OS – Left eye
SYSTEMIC ACTION
- The drug has a widespread influence on the body
- because it is absorbed into the bloodstream
SIDE EFFECT
- Actions other than intended therapeutic effects
- resulting from the pharmacological action of a drug.
- (e.g. headaches, itchiness, things happen because of the drug).
ADVERSE EFFECT
- real bad side effect or specific side effects)
- Negative action resulting from the pharmacological action of a drug, among other factors.
ANTOGONISTIC
one drug diminished the action of another.
- Agent that resists or opposes the action of another agent.
- e.g. antibiotics has an antagonist effect on birth control pills).
- 2 medications together oppose each other or make the effect less or cancel each other out.
AGONIST
-Drug capable of combining with receptors to initiate drug actions
POTENTIATION
- occurs when two drugs administered together
- produce a more powerful response than the sum of their individual effects.
ALLERGIC RESPONSE
(Anaphylactic shock the same thing) - hypersensitive response of the client’s immunological system in the presence of a drug.
o Not the result of pharmacological effects of the drug, but rather a response of the client’s immunological system to the presence of a drug
o Prior sensitization to the drug is generally required
TOXIC EFFECT
: Effects caused by drugs that can result in poisonous injury to a client.
o Those related to the dosage administered
o All drugs are capable of producing toxic effects
o May result from cumulation of drug which occurs when drug is not completely excreted from the body before another dose is given
What is the half life of a drug ?
(The shorter the half-life the more you give it and the longer the half life the less you give it.)
- Half peak level eliminated. (half of the maximum amount dose is eliminated)
- The time it takes for the total amount of the drug to be diminished by ½
- Prescribers will determine the frequency of dosing based on this
- IV has a shorter half life, oral longer
- Short half life means effects wear off faster. Need to give more
- Long half life means will last longer, therefore can give less frequently
What factors affect the half life ??
The shorter the half-life the more frequently you give the drug
The longer the half-life the less frequently you give the drug
What are the following effects of drug ? LOCAL ACTION
A response (to a medication) confined to a specific part of the body.
What route produce most rapid effect ?
IV – most rapid
IM & SQ- speed depends on condition of blood flow
ID - slow, confined to area injected
Oral- rate & Degree depend on GI motility, presence of food, gastric pH & use of other drugs
Is it safe to give medication prepared by another nurse ?
Never
How many times do you need to read a drug lable before administering ?
3 times
What is a loading dose ?
No
How do you safely identify the patient ?
Check the tag on the client’s bed
Check the client’s identification band
Ask the client to state his or her name
Ask parents to tell you the name of their child
Address the person by name before administering the medication
Always double-check a prescription that the clients questions
What is the peak blood concentration ?
B
What should you do if patient refuse to take medication ?
Document in chart that patient refuses to take their medication
Notify the Physician
What are the 7 rights of medication administration ?
Right drug Right dose Right time Right route Right patient Right documentation Right to refuse
When should you withhold a medication ?
When the patient says they have an allergic reaction to a medication
Hold it and let the physician know and get a new order for another medication
What should you do if you cannot read the medication lable ?
M