Paludismo Flashcards

1
Q

Culés son los cuatro fármacos para paludismo?

A

Cloroquina, primaquina, artemetero lumefantrina, sulfadaxina primetramprina

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2
Q

Indicaciones de cloroquina

A

Plasmodium spp

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3
Q

Indicaciones primaquina

A

P. Vivax y ovale

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4
Q

Indicaciones arremeter lumefrantina

A

Profilaxis Y P. Falciparum

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5
Q

Indicaciones sulfadoxina y primetamina

A

P.falciparum

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6
Q

Mecanismo acción de primaquina

A

Interfiere cadena de electrones con la ubiquinana

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7
Q

Meconsmo de acción d cloroquina

A

Se une a la ferroprotoporfirina, forma complejo grupo hemos

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8
Q

Mecanismo de acción de arremeterO lumefantiia

A

Escisión del puente de peróxido hem-herro y generación de radicales libres

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9
Q

Mecanismo de acceso de sulfodaxina pirimetamina

A

Inhibición dihidrofolato reductasa, inhibición dihidropteroato sintetasa

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10
Q

rams de sulfadoxina y primetamina

A

ANEMIA MEGALOBLASTICA
hepatotoxicidad y nefrotoxicidad

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11
Q

RAMS de artemetero lumefantrina

A

PROLONGACIÓN QT
cefalea, vértigo

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12
Q

RAMS de primaquina

A

MOLESTIA ABDOMINAL
METAHEMOGLOBINA

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13
Q

rams de cloró quina

A

bloqueo de rama, PROLONGACIÓN INTERVALO QT, SABOR CULERON, RETINOPATÍA

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14
Q

Fármaco que interaccera con inductores e inhibidos del CYP3A4

A

Arremeter lumefantrina

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15
Q
A
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