Pain, pain, go away Flashcards
Why should pethidine be avoided
accumulation of neurotoxic metabolic can percipitate seizures
Are opioids effective in dental pain
no, rarely
why are NSAIDs a good choice for bone pain
secondary bone tumouts can produce lysis of bone and release of prostaglandins
Co-proxamol is no longer licensed why
toxicity in overdose - although may still be used in patients who find it hard to change
Buprenorphine’s effects are not fully reverse by naloxone because
partical ag and antag properties
why is dipipanone not suitable for prescribing often?
only available in formulations with an antiemetic
alfentanil, remifentanyl and fentanyl are used for analgesia when?
intraoperatively
morphine should not be adminstered more than ……. daily to avoid accumulation
twice
(may be used for pain if patient needs oral solution but experience exacerbation of pain with oramorph
pentazocine is not often used because
hallucinations and may increase cardiac work
MOA of tramadol
opioid and seratanergic and adrenergic pathway enhancement
s/e of giving intrathecal opioids post op
urinary retention, nausea, vomiting, resp depression
three odd side-effects of opioids used long term
hypogonadism and adrenal insufficiency - amenorrhoea, reduced labido, erectile dysfunction
hyperalgesia - increas diffuse and less defined pain, needs specilst referal to then reduce opioids
symptom of opioid overdose
coma, pinpoint pupils, resp depression
if no strength is stated on co-codamol rx what should you supply
8/500
steps to treatment of migrane
normal analgestics 5HT Ag (triptans)
