Pain Management Flashcards
What is Step 1 in the WHO pain ladder?
Non-opioid analgesia ± adjuvants
What is Step 2 in the WHO pain ladder?
Weak opioid analgesia + non-opioid analgesia ± adjuvants
What is Step 3 in the WHO pain ladder?
Strong opioid analgesia + non-opioid analgesia ± adjuvants
Give an example of a non-opioid analgesic agent and an appropriate dose
Paracetamol 1g QDS po
Give 3 examples of weak opioid analgesic agents used for the management of pain
Co-codamol 30/500
Co-dydramol
Tramadol
What are the components of co-codamol 30/500?
Codeine 30mg
Paracetamol 500mg
What are the components of co-dydramol?
Dihydrocodeine
Paracetamol
Give examples of strong opioid analgesic agents
Morphine Oxycodone Fentanyl Diamorphine Buprenorphine
List some adjuvant analgesics which can be used alongside the steps of the WHO pain ladder
NSAIDs e.g. ibuprofen Tricyclics e.g. amitriptyline Gabapentin Bisphosphonates Steroids Radiotherapy
What are the names (drug name and trade name) of the short-acting and the long-acting preparations for morphine?
Short-acting = Oral morphine sulphate solution (Oramorph) Long-acting = Morphine sulphate slow release tablets (MST Continus)
True / False: It is acceptable to use the trade name for morphine when prescribing
True - You can write ‘Oramorph’ on the prescription
How long does Oramorph last for?
4 hours
How many doses of long-acting morphine (morphine sulphate slow release tablets) are given daily?
2 doses - one in the morning and one in the evening
What is the trade name for the short-acting morphine TABLETS which are available?
Sevredol
What dose of Oramorph would you start someone on?
Usually 10mg - If they have been on regular Step 2 analgesia they have already shown they can cope with opioids so this is appropriate. Consider lower dose in people with risk factors.
How frequently would you prescribe Oramorph?
Every 4 hours
How do you work out the dose of long-acting morphine (MST Continus) to give?
Add up the total dose of short-acting Oramorph the patient is taking in one day and divide this into 2 equal doses. For example, if patient is on 10mg of Oramorph 4hrly (6 times per day) they take 60mg of morphine. 60/2 = 30 so the dose of MST Continus is 30mg twice a day (one in the morning and one in the evening)
What might you consider prescribing alongside morphine to reduce the effects of a particular side effect?
Anti-emetic - Morphine commonly causes nausea and vomiting
Metoclopromide 10mg TDS po or s/c
Can you give ‘breakthrough’ morphine to a patient already on long-acting MST Continus?
Yes
What would be your choice of breakthrough analgesia for a patient who is already on long-acting MST Continus?
Oramorph (a short-acting morphine preparation)
How would you work out the dose of breakthrough morphine required for a patient who is daily long-acting MST Continus if they needed extra analgesia for acute pain?
Total daily dose of morphine divided by 6 e.g. if patient is on 60mg of MST Continus daily (split into 2x 30mg doses), then you can prescribe 60/6 = 10mg of Oramorph as breakthrough medication
What is the dosing instruction for PRN ‘breakthrough’ morphine?
Max. 2 doses every 4 hours or 6 doses per 24 hours
What does of codeine is in the standard dose of co-codamol which is prescribed?
30mg (Co-codamol is usually 30/500)
How long does it take for the effects of a morphine patch to wear off?
12-18 hours
If switching from MST Continus BD to Fentanyl patches, how much overlap should there be between the 2 medications?
Take the final tablet of MST Continus at the same time as applying the Fentanyl patch
Tramadol 100mg is equivalent to what dose of oral morphine sulphate?
20mg (conversion is 5:1)
What must be included on a prescription for a controlled drug?
- Prescriber details: Signature, date, prescriber address
- Patient full name, DOB and address
- The name and form of the drug e.g. morphine sulphate tablets
- The dose (e.g. 40mg) or strength (e.g. 10mg/5mL) of the drug
- The total quantity or total number of units written in words and figures
How would you write an outpatient prescription of Morphine Sulphate Tablets (MST) 40mg PO BD?
Morphine sulphate tablets (MST) 40mg PO BD Supply 20 (twenty) 10mg tablets and 20 (twenty) 30mg tablets
What dose of MST Continus is NOT available?
Tablets don’t come in 20mg
List some side effects of NSAIDs
Fluid retention, hypertension Heart failure Bleeding GI disturbance - Ulcers, dyspepsia, nausea and vomiting Nephrotoxocity and renal failure Bronchospasm