pain management Flashcards

1
Q

Allodynia

A

pain associated with non noxious stimulus

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2
Q

Anaesthesia

A

absence of sensation

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3
Q

analgesia

A

absence of pain in presence of a noxious stimulus

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4
Q

distress

A

external display of suffering

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5
Q

hyperaesthesia

A

Increased sensitivity to a stimuli - alodynia and hyperalgesia

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6
Q

hyperalgesia

A

increased sensitivity to a noxious stimuli

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7
Q

hypoalgesia

A

decreased sensitivity to a noxious simuli

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8
Q

nociception

A

transduction, conduction and cns processing of a signal generated by the nociceptors

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9
Q

noxious stimuli

A

painful stimulus

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10
Q

pain

A

unpleasant sensory or physical experience associated with real or potential tissue damage

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11
Q

pain theshold

A

least level of pain that an individual can recognise
if under the threshold - nociceptor not activated

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12
Q

pain tolerance level

A

greatest level of pain that an individual can tolerate

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13
Q

suffering

A

unpleasant emotional state usually internalised not expressed outwardly

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14
Q

windup

A

Sensitisation of the nociceptors and pain pathways that occurs following prolonged severe nociceptive stimuli
- this results in expanced receptive fields to nociception
- increased rate of discharge of the nociceptors
- more pain

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15
Q

pain results in

A

1) behavioural changes
2.) autonomic nervous system stimulation (SNS)
3) neuroendocrine activation
- ACTH => Cortisol
- Catecholamines - Noradrenalin/ adrenalin
- renin - Aldosterone - ADH
- TSH => T4
- Growth hormones
- glucagon/ insulin
+ cytokine release IL1, IL 6 TNF -a

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16
Q

Consequences of pain

A
  • ↑ HR - SNS
  • ↑ coagulability
  • ↑ metabolism
  • ↓ immunity
17
Q

multimodal analgesia

A
  • use of 2 or more analgesis classes together
  • work synergistically
  • improved analgesgia with lower doses - ↓ Side / adverse effects
  • ↓ likelyhood of chronic/wind up pain
  • ↓ NE response
  • ↓ healing time
  • ↓ stress response - ↓ tissue catabolism and maintenance of the immune system
  • ↓ pat
  • ient interference
18
Q

Acute pain

A

pain that begins abruptly and is brief in duration -
-eg superficial laceration - pain resolve when wound is healed

19
Q

Cental pain

A

pain associated with a lesion in the CNS
eg. pain associated with MS

20
Q

chronic pain

A

pain persisting beyond the time frame for healing or pain associated with a chronic pathological process
eg. OA or neoplastic pain

21
Q

inflammatory pain

A

pain associated with tissue damage and inflammation
eg abscess

22
Q

neuropathic pain

A

pain associated with peripheral NS or CNS
eg phantom limb pain

23
Q

neuropathic pain

A

pain associated with peripheral NS or CNS
eg phantom limb pain

24
Q

pathological pain

A

pain that is an exaggerated response for a longer period of time than the normal defence mechanism warrents and is associated with tissue injury
eg, peripheral or central sensitisation

25
physiological pain
normal defence mechanism warning the body of contact with a stimulus that is potentially damaging it initiates behavioural and reflex avoidance strategies
26
somatic pain
sharp stabbing pain associated with skin/joints/muscle/periostium
27
visceral pain
dull aching pain associated with thoracic or abdominal viscera
28
5 physiological parts of pain pathway
1. transduction 2. transmission 3. modulation 4. projection 5. perception
29
What is the Excitatory NT in the spine
Aspartate, Glutamate Substance P
30
what is the excitatory receptors in the spine
NMDA, AMPA
31
Inhibitory NT in the spine
- endogenous opioids - endorphins, dynorphine, encephalin -in hibitory receptors - GABA + glycine exogenous opiods
32
Name different nerve fibres that the primary nerve fiber can connect with
1. Interneurons - excitatory or inhibitory 2. Propriospinal neurone - extend over a few spinal segments - reflex activity 3. Projection neurons. - extend supraspinally - onto brainstem and brain
33
Projection neurons subclassification
1. nociceptive specific (NS) * responds to mechanical or thermal input from Aa or C type fibres q - respond to impulses in a discrete areas 2. wide dynamic range - i - responds to nociceptive input and non nociceptive input - - responds to large area 3. complex - integrate somatic and visceral afferent activity