pain and pca Flashcards
origins of pain
treated with different drugs
nociceptive: non opioids, opioids and adjuvant therapy
neuropathic: adjuvant (anticonvulsants, antidepressants, etc)
types of pain
acute, chronic malignant (cancer), chronic nonmalignant
treatment varies
gate control theory
gating mechanism at dorsal horn of spinal cord
gate open = pain impulse gets through to brain and pt perceives; a alpha and a beta fiber stim (large diameter nerve fibers - rubbing, p, hot, cold)
gate closed = pain impulse cant get through and person does not perceive
decrease pain perception: distraction provides adequate sensory input at brainstem, avoid anx producing stimuli at cerebral cortex (teach to know what to expect, provide reassurance)
no brain no pain -> nurses can minimize impulse getting to brain
two pathways for pain transmission
Pathway for “fast pain” is the A-delta fibers.
Pathway for “slow pain” is the C-fibers.
pain threshold
least amount of pain a person can recognize. (Does not vary from person to person)
pain tolerance
ability to withstand pain stimuli without demonstrating physical signs of pain. (Varies widely from person to person, and event to event)
addiction
psychological
Overwhelming involvement with obtaining a drug for psychic effects.
tolerance
physiological
The opioid begins to lose its effectiveness & larger doses are necessary. This would happen to everyone who was on opioids for an extended period. NOT to be confused with addiction.
dependence
physiological
Withdrawal symptoms would occur if the drug were to be withdrawn abruptly. This would happen to everyone who was on opioids for an extended period. NOT to be confused with addition.
opioids
morphine is drug of choice
avoid merperidine for >2days
percocet is oxycodone + acetaminophen
antidote = naloxone
opioids except for codeine do NOT have ceiling effect
non opioids
NSAIDs and tylenol (no antiinflam)
ceiling effect
adjuvant therapy
gabapentin
neuropathic pain
opioids SE
Sedation – will develop tolerance to this (? Caffeine, if not contraindicated)
Pruritis – will develop tolerance to this (? Administer Benadryl)
Urinary retention – will develop tolerance to this (I&O cath prn)
Constipation – the only side effect that the patient will NOT develop tolerance to; the good nurse is always vigilant about the patient’s bowel patterns when he is on opioids; the constipation could get to be a bigger problem than the pain!
Resp depression is biggest fear but VERY uncommon; be most vigilant when administering an opioid to an ‘opioid naïve’ patient.
non opioids SE
NSAIDS, including ASA – GI upset, increased bleeding time & possible renal problems
COX2 inhibitors – claim to fame was avoidance of the above side effects; however, several that were originally marketed were found that these drugs increase likelihood of MI & CVA in at-risk patients. (One currently on market = celecoxib)
acetaminophen (Tylenol) – minimal GI upset; people with stomach problems love this drug; has NO anti-inflammatory properties; works by inhibiting prostaglandin synthesis (prostaglandins are the ‘bad guys’); IMPORTANT: Take no more than 4 Gm of Tylenol in 24 hrs (hepatotoxic); antidote = acetylcysteine (Mucomyst).
PCA general
contain opioid, also now seeing ketamine
IV, epidural, or both -> always monitor excite site (infection)
only pt pushes (too sleepy = higher risk for resp dep so no pushy)