Pain Flashcards
What is nociceptive pain
appropriate physiological response to painful stimulus via a working nervous system
What is neuropathic pain
inappropriate response caused by a dysfunction in the nervous system
symptoms of neuropathic pain
shooting or burning pain sensation tingling & numbness allodynia - pain to a stimulus that is not normally painful (light touch) hyperalgesia - increase in pain response that is normally painful (pin prick)
causes of neuropathic pain
spinal cord injury MS stroke diabetic neuropathy trigeminal neuralgia
for neuropathic pain, what drugs would be offered? (except trigeminal neuralgia)
amitriptyline duloxetine gabapentin pregabalin
1st line Mx for trigeminal neuralgia
Carbamazepine
mode of action for amitriptyline
Inhibits reuptake of noradrenaline & serotonin
S/E amitriptyline
constipation
weight gain
dry mouth
mydriasis
sedation
hypotension
mode of action for duloxetine
inhibits reupatke of serotonin and noradrenaline
S/E duloxetine
nasuea
dry mouth
constipation
somnolence
loss of oappetite
hyperhidrosis
mode of action for gabapentine
inhibits Ca2+ channels
S/E gabapentin
somnolence
dizziness
peripheral oedema
weight gain
ataxia
mode of action for pregabalin
inhibits Ca2+ channels
S/E for pregabalin
somnolnece
dizziness
peripheral oedema
weight gain
ataxia
what is & symptoms of complex regional pain
neuropathic pain
usually after surgery or injury affecting arm & leg
disproportionate pain
swelling
skin changes
motor dysfunctions
