Pain

Question 1

The breakthrough dose of pain relief is what fraction of the total daily dose of long-acting pain relief?

Answer 1

one-sixth of the total daily dose

Question 2

Patients prescribed strong pain relief should also be prescribed what class of drug?

Answer 2

laxatives

Question 3

What analgesic agents should be used in patients with renal impairment

Answer 3

Mild-moderate renal impairment = Oxycodone

severe renal impairment = alfentanil, buprenorphine and fentanyl

Question 4

Pain relief options for metastatic bone pain

Answer 4

May respond to:
- strong opioids
- bisphosphonates
- radiotherapy

Question 5

By how much should you increase the dose of opioids?

Answer 5

30-50%.

Question 6

Convert dose of oral codeine or tramadol to oral morphine

Answer 6

divide by 10

Question 7

What side effects are more prominent with oxycodone than with morphine?

Answer 7

constipation.

Question 8

What side effects are more prominent with morphine than with oxycodone?

Answer 8

sedation
vomiting
pruritis

Question 9

Conversion of oral morphine dose to oral oxycodone dose

Answer 9

Divide by 1.5-2

Question 10

A transdermal fentanyl 12 microgram patch equates to approximately what dose of oral morphine?

Answer 10

30 mg oral morphine daily

Question 11

A transdermal buprenorphine 10 microgram patch equates to approximately how much oral morphine?

Answer 11

24 mg oral morphine daily

Question 12

Dose conversion from oral to subcutaneous morphine

Answer 12

Divide by 2

Question 13

Dose conversion from oral morphine to subcutaneous diamorphine

Answer 13

Divide by 3

Question 14

Dose conversion from oral oxycodone to subcutaneous diamorphine

Answer 14

Divide by 1.5