Pain Flashcards
Types of pain
Acute
Chronic
How can you treat bone pain
Non-medications:
Behaviour modifications, movement aids, home adaptations
Bisphosphonates
Strong opiods
Radiotherapy (most effective specific
treatment for cancer induced bone pain)
Radiotherapy helps what percentage of patients with cancer induced bone pain?
60 percent
Maximum effect at 6 weeks
WHO Analgesic Ladder
Step 1 - non-opioid
Step 2 - weak opioid + non-opioid
Examples of step 2 opioids
Codeine, dihydrocodeine
Tramadol
Buprenophine (but can become step 3 at higher doses)
Examples of step 3 opiods
Morphine
Alfentanil
Codeine to morphine enzyme for conversion
Cytochrome P450 CYP 2D6
Codeine vs morphine equation
Oral codeine is 10 times less potent than oral morphine
e.e. codeine 240mg = 24mg of morphine
Weak opiods + non opiod examples
Co-codamol
Usually patients are on moderate release prep
When might you get drowsiness as a side effect of pain medication
Drowsiness at initiation, dose increases or reductions
Other SE of opioids and how you can manage it
Constipation - prescribe a laxative
Nausea - usually self resolves with anti emetic, doesn’t come back
Drowsiness - lower the dose
Opioid toxicity side effects
Sedation
Confusion
Hallucinations
Myoclonic jerks
Pinpoint pupils
Coma