Paget's Disease

Question 1

What is Paget’s disease of the nipple?

Answer 1

An eczema like rash on the nipple that is associated with malignancy

Question 2

What is paget’s disease of the nipple suggestive of?

Answer 2

An underlying ductal carcinoma in situ

Question 3

What is the presentation of paget’s disease of the nipple?

Answer 3

Eczema like rash on the nipple that is itchy, red and inflamed
Bloody nipple discharge
Burning sensation or pain in the nipple
Retraction or inversion
Palpable breast lump
Non-healing ulcers

Question 4

What are the differentials of paget’s disease of the nipple?

Answer 4

Atopic dermatitis
Contact dermatitis
Intraductal papilloma
Mastitis
Breast abscess
Psoriasis

Question 5

What investigations are used to diagnose paget’s disease of the nipple?

Answer 5

Physical breast examination
Mammogram
Breast ultrasound
Biopsy of the skin
Nipple discharge cytology
MRI

Question 6

What is the management of paget’s disease of the nipple?

Answer 6

Surgery
- Mastectomy
- Modified radical mastectomy
- Lumpectomy
Chemotherapy
Radiotherapy

Question 7

What is a modified radical mastectomy?

Answer 7

Where the entire breast, as well as axilliary lymph node is removed