Page 4 (FSG, Alport Syn, Diabetic Neph) Flashcards
Only a certain number and areas of the glomerulus are affected.
Focal Segmental Glomerulosclerosis
The disease is caused by the disruption of podocytes associated with analgesic and heroin abuse and AIDS.
Focal Segmental Glomerulosclerosis
IgM and C3 are seen in the undamaged glomerulus
Focal Segmental Glomerulosclerosis
an inherited disorder affecting the glomerular basement
membrane.
Alport Syndrome
Alport Syndrome gene
Sex-linked
Autosomal
Alport Syndrome gender
Male>Female
glomerular basement membrane has a lamellated appearance with areas of thinning.
Alport Syndrome
prognosis ranges from mild symptoms to persistent hematuria and renal insufficiency in later life to the nephrotic syndrome and end-stage renal disease.
Alport Syndrome
also known as Kimmelstiel-Wilson disease
Diabetic Nephropathy
currently the most common cause of end-stage renal disease
Diabetic Nephropathy
increased proliferation of mesangial cells and increased deposition of cellular and noncellular material within the glomerular matrix resulting in accumulation of solid substances around the capillary tufts.
Diabetic Nephropathy
_____________ is important to
detect the onset of Diabetic Nephropathy.
Microalbumin monitoring